Neurophysiological and Functional Mechanisms of Motor Control and Learning

Transcranial Direct Current Stimulation Clinical Trial

Official title: Neurophysiological and Functional Mechanisms of Motor Control and Learning

Status Completed

Clinical Trial Summary

Noninvasive stimulation of the central nervous system, including transcranial magnetic stimulation (TMS) and transcranial direct current stimulation (tDCS), has been increasingly used in the investigation of cortical plasticity. The purpose of our study is to understand mechanistically-at the neurophysiological and systems levels-how the brain learns new motor skills. We propose to study the acquisition, consolidation, and retention of motor skill learning in healthy subjects. At the behavioral level, we will use movement kinematics to quantify and characterize movement, which allow us to infer functional strategies used by the brain to reduce movement errors. At a neurophysiological level, we will use TMS to document changes in cortical circuitry, which will allow us to infer neuroplastic changes possibly subserving these strategies. At a systems level, we will enhance motor system excitability using tDCS, which will enable us to infer the contribution of the stimulated area to the motor system's ability to learn new skills.

Clinical Trial Description

n/a

Related Conditions & MeSH terms

• Transcranial Direct Current Stimulation

• NCT number: NCT03190590
• Study type: Interventional
• Source: NYU Langone Health
• Status: Completed
• Phase: N/A
• Start date: March 20, 2018
• Completion date: July 18, 2018