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Apatinib Plus Irinotecan as Second-line Treatment in AGC or EGJA

Metastatic Gastric Adenocarcinoma Clinical Trial

Official title:
A Prospective, Multicenter Clinical Study of Apatinib Plus Irinotecan as Second-line Treatment in Locally Advanced or Metastatic Gastric or Gastroesophageal Junctional Adenocarcinoma

Clinical Trial Summary

This is a prospective, multicenter, single-group clinical study of Apatinib Plus Irinotecan as second-line treatment in locally advanced or metastatic gastric or gastroesophageal junctional adenocarcinoma.

Clinical Trial Description

This is a prospective, multicenter, single-group clinical study of Apatinib Plus Irinotecan as second-line treatment in locally advanced or metastatic gastric or gastroesophageal junctional adenocarcinoma. Interventions: Irinotecan: 180mg/m2, ivgtt,given on the first day; Apatinib: initial dose: 250mg,oral,once a day, after meal ( try to take the medicine at the same time each day). Repeat the therapeutic schedule every 3 weeks till progressive disease or intolerable toxicities. Primary Outcome Measure: PFS. Secondary Outcome Measures: OS, ORR, DCR. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT03116555
Study type Interventional
Source China Medical University, China
Contact YunPeng Liu, PhD
Phone 86-24-83282312
Email cmuliuyunpeng@hotmail.com
Status Recruiting
Phase Phase 2
Start date April 5, 2017
Completion date September 2020
View Details
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