Interactable Malignant Perineal Pain Clinical Trial
Official title:
The Role of Selective Thermal Radiofrequency Saddle Rhizotomy In Managing Interactable Malignant Perineal Pain: A Comparative Study
The control of perineal malignant pain is difficult and challenging for pain physicians.
Different modalities have been tried to treat this complex pain syndrome including
pharmacotherapy and interventional therapy.
Neuroaxial phenol rhizolysis is simple and cheap option. However; for patients with pelvic
or rectal neoplasms and intact bowel and bladder sphincteric functions, there are
neurosurgical recomendations of selective sacral nerve roots rhizotomy blockade "as an
alternative to chemical saddle rhizotomy".
40 selected patients were randomly allocated into 2 groups "20 patients each"
Group 1 "RF group": in which patients underwent thermal radio Frequency, selective
(unilateral S3, bilateral S4 and S5) saddle rhizotomy.
Group 2 "phenol group": in which patients underwent hyperbaric chemical saddle rhizotomy
using 6% phenol in glycerin.
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