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Clinical Trial Summary

The purpose of this study is to plan for future clinical trials in patients with metastatic urological cancers. Diluted iodinated contrast will be injected intra-tumorally under CT fluoroscopy guidance into bone, lymph node, soft tissue and liver metastases in subjects with metastatic prostate cancer, urothelial carcinoma, or renal cell carcinoma. Pre- and post-injection CT images will be obtained to determine the injection parameters needed for optimal distribution throughout metastases of a given size. A biopsy of the metastatic site will also be obtained to validate expression of the receptor CD155.


Clinical Trial Description

n/a


Study Design


Related Conditions & MeSH terms


NCT number NCT03071328
Study type Interventional
Source Duke University
Contact
Status Completed
Phase Early Phase 1
Start date January 8, 2018
Completion date April 30, 2021

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