Diagnosis Prosthetic Joint Infection Clinical Trial
Official title:
Benefit of Synovial Aspiration and Serological Testing in Two-stage Revision Arthroplasty of Prosthetic Joint Infection
The two-stage protocol is gold standard in terms of infection control treating prosthetic
joint infections of total hip and total knee arthroplasty. The antibiotic pause for
diagnostic reasons before reconstruction (stage two) is discussed concerning persistence of
infection and development of resistant bacterial strains. Serological markers and synovial
analysis are common use to exclude persistence of infection.
The investigators therefore asked 1) is the serological testing of c-reactive protein and
leukocytes a valuable tool to predict a persistence of infection and 2) what is the role of
synovial aspiration of PMMA Spacers on hip and knee joints.
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