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Clinical Trial Summary

The purpose of the study is to assess the efficacy of high-frequency non-invasive ventilation on apnea duration, carbon dioxide clearance and oxygen delivery in healthy subjets and patients with lung disease.


Clinical Trial Description

High frequency ventilation (HF-V) allows to ensure oxygen delivery and carbon dioxide clearance despite the absence of thoracic movement in anesthetized, invasively ventilated subjects. This same technique could be applied by a non-invasive interface (HF-NIV), allowing to obtain a prolonged apnea (absence of thoraco-abdominal respiratory movements) in awaken subjects. Such an application would be of interest for several clinical applications, e.g. lung imaging and radio-therapy treatment on lung cancer. The purpose of the study is to assess the effect of different HF-NIV setting on the apnea duration, carbon dioxide clearance and oxygen delivery in healthy subjets and patients with lung diseases. ;


Study Design


Related Conditions & MeSH terms


NCT number NCT02712190
Study type Interventional
Source Centre Hospitalier Universitaire Vaudois
Contact Alban Lovis, MD
Email alban.lovis@chuv.ch
Status Recruiting
Phase N/A
Start date March 2016
Completion date September 2022

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