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Discovery of New Early Detection Biomarkers of Acute Respiratory Distress Syndrome — ARDS  

Acute Respiratory Distress Syndrome Clinical Trial

Official title:
Discovery of New Early Detection Biomarkers of Acute Respiratory Distress Syndrome

Clinical Trial Summary

The goal of this project is to find a series novel biomarkers by differential proteomic techniques that can improve the early diagnosis and develop a more efficient therapy to enhance ARDS patient survival rate.

Clinical Trial Description

Acute respiratory distress syndrome(ARDS) has a very poor prognosis and high mortality. To improve the early diagnosis of ARDS, there is an urgent need for novel biomarkers of ARDS. The goal of this project is to find a series novel biomarkers by differential proteomic techniques that can improve the early diagnosis and develop a more efficient therapy to enhance ARDS patient survival rate. Clinical data and blood sample were recorded before treatment and after treatment. Acute Physiology And Chronic Health Evaluation III (APACHE III) scores were calculated at enrolment. Studying blood specimens from different period ARDS patients by proteomic analysis. It can provide information on a complex composition of proteins that are differentially expressed, which could be used for discovering high sensitivity and specificity ARDS biomarker. ;

Study Design

Observational Model: Cohort, Time Perspective: Prospective

Related Conditions & MeSH terms

  • Acute Lung Injury
  • Acute Respiratory Distress Syndrome
  • Respiratory Distress Syndrome, Adult
  • Respiratory Distress Syndrome, Newborn
  • Syndrome
Clinical Trial Details
NCT number NCT02625064
Study type Observational
Source Xiangya Hospital of Central South University
Contact Pinhua Pan, MD, Doctor
Phone +86 13574810968
Email pinhuapan668@126.com
Status Not yet recruiting
Phase N/A
Start date January 2016
Completion date January 2019
View Details
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