Functional Movement-power Training for Children With Developmental Coordination Disorder: A Randomised Controlled Trial

Developmental Coordination Disorder Clinical Trial

Official title:

Enhancing Neuromuscular Performance and Central Nervous System Plasticity Through Functional Movement-power Training to Improve Balance Strategies in Children With Developmental Coordination Disorder: A Randomised Controlled Trial

Clinical Trial Details — Status: Active, not recruiting

Administrative data

• NCT number: NCT02393404
• Other study ID #: 27100614
• Status: Active, not recruiting
• Phase: N/A
• First received: March 9, 2015
• Last updated: March 18, 2015
• Start date: March 2014
• Est. completion date: March 2017

Study information

• Verified date: March 2015
• Source: The University of Hong Kong
• Contact: n/a
• Is FDA regulated: No
• Health authority: Hong Kong: Ethics Committee
• Study type: Interventional

Clinical Trial Summary

Objective: To compare the effectiveness of functional movement-power training (PT-FMT), functional movement training (FMT) alone and no intervention in improving balance strategies and performance among children with developmental coordination disorder (DCD).

Design: A randomised controlled clinical trial. Sample: 87 children with DCD. Interventions:

12 weeks of PT and FMT or FMT alone in the two intervention groups.

Major outcomes: Sensory organisation test - balance strategy and composite scores; Movement Assessment Battery for Children - total impairment score and balance subscore; hand-held dynamometer measurements of lower limb muscle strength and time to peak force.

Description:

With the growing numbers of children with dyspraxia in Hong Kong, the focus of paediatric rehabilitation services has shifted from severe motor disorders (e.g., cerebral palsy) to relatively minor motor problems such as developmental coordination disorder (DCD). Evidence-based treatment strategies must be developed to suit this changing need. Children diagnosed with DCD are characterised by marked impairment in motor functions. Poor balance ability is a major concern because it may predispose children to falls and affect their motor skill development. At present, rehabilitation regimes for DCD-affected children use functional movement training (FMT) to induce neural plastic changes in the central nervous system (CNS) and thus enhance functional (balance) performance. Less emphasis is placed on treating the neuromuscular impairments that might also affect functional outcomes. Recently, the investigators research team discovered that slowed hamstring muscle force production, a neuromuscular deficit, may be one of the causes of poor balance strategies in children with DCD, but no effective treatment strategy has yet been examined. Power training (PT) has been found to be effective in increasing the speed of muscle force production and balance in adults through various neuromuscular mechanisms. In this study, the investigators intend to treat both the CNS and peripheral neuromuscular deficits in DCD-affected children. Therefore, the investigators will incorporate PT into a conventional FMT regime. The investigators hypothesise that balance strategies and functional performance in children with DCD will be improved most by treating both the CNS and neuromuscular deficits. This hypothesis will be supported by the finding that PT with FMT is superior to FMT alone in improving balance strategies and functional performance in children with DCD.

Objective: To compare the effectiveness of PT-FMT, FMT alone and no intervention in improving balance strategies and performance among children with DCD. Design: A randomised controlled clinical trial. Sample: 87 children with DCD. Interventions: 12 weeks of PT and FMT or FMT alone in the two intervention groups.

Major outcomes: Sensory organisation test - balance strategy and composite scores; Movement Assessment Battery for Children - total impairment score and balance subscore; hand-held dynamometer measurements of lower limb muscle strength and time to peak force.

Anticipated results and clinical significance: DCD-affected children who receive FMT together with PT will have the best balance performance outcomes. If the results are positive, this training programme could be readily transferrable to clinical practice. This could have positive socio-economic implications, such as shorter treatment periods and reduced healthcare costs.

Recruitment information / eligibility

• Status: Active, not recruiting
• Enrollment: 87
• Est. completion date: March 2017
• Est. primary completion date: March 2017
• Accepts healthy volunteers: No
• Gender: Both
• Age group: 6 Years to 10 Years

Eligibility

Inclusion Criteria:

1. a formal diagnosis of DCD based on the Diagnostic and Statistical Manual of Mental Disorders (DSM-IV-TR)

2. a gross motor composite score = 42 on the Bruininks-Oseretsky Test of Motor Proficiency

3. 6-10 years old

4. attending a mainstream school; and (5) no intellectual impairment.

Exclusion Criteria:

1. diagnosis of an emotional, neurological or other movement disorder

2. significant congenital, musculoskeletal or cardiopulmonary disorders that might affect motor performance

3. receiving active treatments including traditional Chinese medicine

4. disruptive behaviour

5. unable to follow instructions thoroughly.

Study Design

Allocation: Randomized, Endpoint Classification: Efficacy Study, Intervention Model: Parallel Assignment, Masking: Single Blind (Outcomes Assessor), Primary Purpose: Treatment

Related Conditions & MeSH terms

• Ataxia
• Developmental Coordination Disorder
• Motor Skills Disorders

Intervention

Other:
• PT-FMT
Physiotherapeutic functional movement-power training
• FMT alone
Physiotherapeutic power training

Locations

Country	Name	City	State
Hong Kong	University of Hong Kong	Pokfulam

Sponsors (1)

Lead Sponsor	Collaborator
The University of Hong Kong

Country where clinical trial is conducted

Hong Kong, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Changes in sensory organisation test balance strategy		Baseline (0 month), 3-month post-intervention (3 months), and 3-month follow-up (6 months)	No
Primary	Changes in sensory organisation test composite scores		Baseline (0 month), 3-month post-intervention (3 months), and 3-month follow-up (6 months)	No
Secondary	Changes in Movement Assessment Battery for Children total impairment score		Baseline (0 month), 3-month post-intervention (3 months), and 3-month follow-up (6 months)	No
Secondary	Changes in Movement Assessment Battery for Children balance subscore		Baseline (0 month), 3-month post-intervention (3 months), and 3-month follow-up (6 months)	No
Secondary	Changes in hand-held dynamometer measurements of lower limb muscle strength		Baseline (0 month), 3-month post-intervention (3 months), and 3-month follow-up (6 months)	No
Secondary	Changes in hand-held dynamometer measurements of lower limb muscle time to peak force		Baseline (0 month), 3-month post-intervention (3 months), and 3-month follow-up (6 months)	No