Clinical Trials Logo
  1. Home
  2. Other
  3. NCT02158039

Endoscopic Ultrasound-guided Ethanol Injection of Pancreatic Cystic Neoplasms

Neoplasms, Cystic, Mucinous, and Serous Clinical Trial

Official title:
Endoscopic Ultrasound-guided Ethanol Injection of Pancreatic Cystic Neoplasms

Clinical Trial Summary

Cystic tumors of the pancreas are fluid-filled growths. They are often treated by surgical removal. A safe and effective non-surgical treatment is desirable. Ethanol (alcohol) injection may treat cysts by killing the lining cells of the cyst, and is an accepted treatment for cysts of other organs. In this study, participants with pancreatic cysts underwent endoscopic ultrasound (EUS) guided ethanol injection of pancreatic cysts. This was a pilot study to assess safety and efficacy.

The hypotheses of this study were 1) complications of EUS guided ethanol injection requiring hospitalization will occur in <10% of subjects, and 2) EUS guided ethanol injection, with retreatment as necessary, will ablate at least 50% of pancreatic cysts.

Clinical Trial Description

EUS is performed via the mouth under sedation. After a needle is placed into the pancreas cyst under EUS guidance, an ethanol solution is placed into the cyst via the needle. The ethanol solution is withdrawn and new ethanol injected, and this process is continued for 5 minutes, repeatedly washing the cyst with the ethanol solution.

After this treatment, usual clinical follow-up is obtained including assessments of the cyst by CT or MRI scans. If a cyst of significant size persists, additional EUS-guided ethanol injections of the cyst were offered. ;

Study Design

Related Conditions & MeSH terms

  • Neoplasms
  • Neoplasms, Cystic, Mucinous, and Serous
Clinical Trial Details
NCT number NCT02158039
Study type Interventional
Source Mayo Clinic
Contact
Status Completed
Phase Phase 1
Start date June 2004
Completion date September 2015
View Details
See also
  Status Clinical Trial Phase
Active, not recruiting NCT01037049 - Optimum Timing for Surgery After Pre-operative Radiotherapy 6 vs 12 Weeks Phase 2
Active, not recruiting NCT01995942 - Molecular, Pathologic and MRI Investigation of the Prognostic and Redictive Importance of Extramural Venous Invasion in Rectal Cancer (MARVEL) Trial
Withdrawn NCT01057355 - Endoscopic Ethanol Ablation of Communicating Pancreatic Cystic Neoplasms Phase 1
Completed NCT02330497 - Efficacy and Safety of Radiofrequency Ablation in Pancreatic Neuroendocrine and Cystic Tumor N/A
Active, not recruiting NCT02005965 - Low Rectal Cancer Study (MERCURY II)