Castration-resistant Prostate Cancer Clinical Trial
Official title:
F-choline PET in Early Response Assessment for Castration Resistant Prostatic Cancer Treated by Abiraterone Acetate or Enzalutamide
Until today no current diagnostic tool exists to identify an early objective response when
patients with castration-resistant prostate cancer were treated by abiraterone acetate or
enzalutamide. According to the Prostate Cancer Working Group, the investigators have to wait
12 weeks before the first evaluation. To know soon that the treatment is effective will be
decisive for the oncologist, even more in palliative situation where second effects can't be
imposed to patients.
In post-docetaxel, the F-choline PET-CT could be used to assess the response of this new
therapy. Moreover, the investigators suppose that we can assess an early stage if there is
an objective therapeutic response, at 6 weeks of treatment, in order to avoid unnecessarily
and expansive treatment.
The aim of this study is to assess if it is possible to determine early (6 weeks of
treatment)if a F-choline PET-CT could predict the response to abiraterone acetate or
enzalutamide in post-docetaxel.
n/a
Endpoint Classification: Efficacy Study, Intervention Model: Single Group Assignment, Masking: Open Label, Primary Purpose: Diagnostic
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