Acute Decompensated Heart Failure (ADHF) Clinical Trial
Official title:
Non-Invasive Pulmonary Monitoring in Patients With Cardiogenic Pulmonary Congestion and Edema
The aim of the study is to determine the feasibility of collecting respiratory parameters during recompensation following ADHF (Acute Decompensated Heart Failure)with non-invasive measurements. This could lead to a better understanding of how respiratory parameters may change during re-compensation therapy and could also be a comfortable method for patients.
The study is designed as a single-center, open, interventional, observational study
according to clause §23b of the German Medical Device Act (MPG). The study will recruit 50
patients suffering from cardiogenic pulmonary congestion and edema including ambulant
patients and patients of intensive care.
We will investigate whether respiratory parameters during re-compensation are related to the
therapy effects and changes in pulmonary congestion status. This study will collect data in
an observational and clinical setting in the re-compensation phase of ADHF.
Correlation between measured lung and respiratory parameters and standard clinical
parameters characterizing stages of re-compensation will be undertaken. Standard clinical
parameters may include diuretics and other cardiac medication dose frequency, weight, heart
rate, respiratory rate, chest x-rays (when routinely performed), symptoms such as shortness
of breath or fatigue, biomarkers such as brain natriuretic peptide (BNP), stroke volume,
cardiac output, and oxygen requirements.
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Intervention Model: Single Group Assignment, Masking: Open Label, Primary Purpose: Basic Science
| Status | Clinical Trial | Phase | |
|---|---|---|---|
| Terminated |
NCT01474200 -
Study of Heart Failure Hospitalizations After Aquapheresis Therapy Compared to Intravenous (IV) Diuretic Treatment
|
N/A |