Foetal Differences Between Healthy and Schizophernic Parents Clinical Trial
Official title:
Prospective Ultrasonographic and Magnetic Resonance Imaging (MRI) Assessment of General and Brain Fetal Development in Offspring of Schizophrenic Patients
Schizophrenia is a common disorder with a lifetime prevalence of about 1%.Genetic studies
strongly suggest a genetic component to the inheritance of schizophrenia. Structural
neuroimaging studies have provided consistent evidence for brain abnormalities in
schizophrenia. The timing of brain abnormalities in schizophrenia has not been determined
yet.
The investigators hypothesize that brain structural changes can be detected in neonatal
life. The investigators hypothesize that offspring of schizophrenic patients will have
higher rates of brain structural changes in the neonatal period. The investigators propose
to study early development of fetuses in offspring of patients with schizophrenia. The study
is a multi-center prospective trial.
n/a
Allocation: Non-Randomized, Intervention Model: Parallel Assignment, Masking: Open Label, Primary Purpose: Screening