Safety and Preliminary Efficacy of the Treatment of Kidney Allografts With Curcumin-containing Preservation Solution

End Stage Renal Failure With Renal Transplant Clinical Trial

Status Recruiting

Clinical Trial Summary

The safety and preliminary efficacy of the addition of an aqueous curcumin-cyclodextrin complex (CDC) solution to graft perfusion solution is studied. CDC has proved safe and highly effective in preventing primary graft non-function, delayed graft function and chronic dysfunction in pre-clinical kidney transplantation animal models. The hypothesis is that addition of CDC to the graft perfusion solution will decrease the incidence of delayed graft function in human kidney transplantation subjects.

Clinical Trial Description

n/a

Study Design

Allocation: Randomized, Endpoint Classification: Safety/Efficacy Study, Intervention Model: Parallel Assignment, Masking: Open Label, Primary Purpose: Prevention

Related Conditions & MeSH terms

• End Stage Renal Failure With Renal Transplant
• Kidney Failure, Chronic

• NCT number: NCT01285375
• Study type: Interventional
• Source: Helsinki University Central Hospital
• Contact: Jakob Stenman, MD, PhD
• Phone: +35894711
• Email: jakob.stenman@hus.fi
• Status: Recruiting
• Phase: Phase 1
• Start date: January 2011
• Completion date: December 2012