Anomia (Word-retrieval Impairment) Clinical Trial
— CATSOfficial title:
Chronic Aphasia - Improved by Intensive Training and Electrical Brain
The purpose of this study is to determine if non-invasive electrical brain stimulation can enhance the out of intensive language therapy in chronic aphasia
Status | Recruiting |
Enrollment | 40 |
Est. completion date | December 2014 |
Est. primary completion date | August 2014 |
Accepts healthy volunteers | No |
Gender | Both |
Age group | 18 Years to 70 Years |
Eligibility |
Inclusion Criteria: - right-handedness - single first time left-hemisphere stroke - fluent- or non-fluent chronic aphasia (more than six months post-stroke) - anomia (PR>10 and PR<60 Aachen Aphasia Naming Subtest) - native German Speaker Exclusion Criteria: - more than one stroke - alcoholism, severe psychiatric conditions, other neurological conditions - other non-treated medical problems, severe microangiopathy - pregnancy |
Allocation: Randomized, Endpoint Classification: Efficacy Study, Intervention Model: Parallel Assignment, Masking: Double Blind (Subject, Investigator, Outcomes Assessor), Primary Purpose: Treatment
Country | Name | City | State |
---|---|---|---|
Germany | Charite, University Medicine, Dept. of Neurology | Berlin |
Lead Sponsor | Collaborator |
---|---|
Charite University, Berlin, Germany | German Federal Ministry of Education and Research |
Germany,
Type | Measure | Description | Time frame | Safety issue |
---|---|---|---|---|
Primary | Boston Naming Test | Change of naming score from baseline (day 1 of study) to immediately after 2-week intervention period (post-testing) | No | |
Secondary | Boston Naming Test | The follow-up will be administered to assess the stability of the treatment gains | Change of naming score from post-testing (after end of intervention) to 3 months after the intervention (follow-up) | No |
Secondary | Naming performance during functional magnetic resonance scanning | assessed during overt picture naming task | Change of naming score from baseline (day 1 of study) to immediately after 2-week intervention period (post-testing) | No |
Secondary | Naming performance during functional magnetic resonance imaging | assessed during overt picture naming task | Change of naming score from post-testing (after end of intervention) to 3 months after the intervention (follow-up) | No |