Postoperative Cognitive Dysfunction After Total Knee or Hip Replacement Surgery in Fast-track Set-up

Postoperative Cognitive Dysfunction Clinical Trial

Official title:

Postoperative Cognitive Dysfunction After Total Knee or Hip Replacement Surgery in Fast-track Set-up

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT01103752
• Other study ID #: H-3-2009-096
• Status: Completed
• Phase: N/A
• First received: April 13, 2010
• Last updated: December 13, 2011
• Start date: October 2009
• Est. completion date: December 2011

Study information

• Verified date: December 2011
• Source: Rigshospitalet, Denmark
• Contact: n/a
• Is FDA regulated: No
• Health authority: Denmark: The Danish National Committee on Biomedical Research Ethics
• Study type: Observational

Clinical Trial Summary

The aim of this study is to quantify the incidence of postoperative cognitive dysfunction in the elderly patient (>60y) after total hip or knee replacement surgery. The hypothesis is that the fast-track methodology with a mean hospital stay less than 3 days will help to minimize this reduction in memory and concentration.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 225
• Est. completion date: December 2011
• Est. primary completion date: September 2011
• Accepts healthy volunteers: Accepts Healthy Volunteers
• Gender: Both
• Age group: 60 Years and older

Eligibility

Inclusion Criteria:

• 60 years of age or above

• ASA classification 1-4

• undergoing fast-track hip or knee replacement

Exclusion Criteria:

• anaesthesia within the past 90 days

• daily consumption of sleep or anxiety medication

• more than 35 units of alcohol per week

• lack of proper verbal and reading skills, Danish

• Serious hearing or visual impairment

• Mini mental status evaluation (MMSE) < 24

• Parkinsons Disease or other neurological disease causing functional impairment

Study Design

Time Perspective: Prospective

Related Conditions & MeSH terms

• Cognition Disorders
• Postoperative Cognitive Dysfunction

Intervention

Other:
• no intervention, descriptive study
no intervention, descriptive study

Locations

Country	Name	City	State
Denmark	The Lundbeck Centre for fast-track hip/knee surgery	Copenhagen

Sponsors (2)

Lead Sponsor	Collaborator
Lene Krenk	Lundbeck Foundation

Country where clinical trial is conducted

Denmark,