Clinical Trials Logo

Clinical Trial Summary

Locally advanced non-small cell lung cancer can be treated successfully with chemotherapy and radiation. However, the cure rate is low.

This study is carried out to find out whether giving radiotherapy at a higher dose over fewer treatment sessions with intensity modulated radiotherapy (IMRT) can improve the treatment outcome.

This study aims to recruit 43 patients from National University Hospital and Tan Tock Seng Hospital over a period of about 2 years.


Clinical Trial Description

n/a


Study Design

Endpoint Classification: Efficacy Study, Intervention Model: Single Group Assignment, Masking: Open Label, Primary Purpose: Treatment


Related Conditions & MeSH terms


NCT number NCT00938418
Study type Interventional
Source National University Hospital, Singapore
Contact Ivan Tham, MD
Phone 6567724870
Email ivan_wk_tham@nuh.com.sg
Status Recruiting
Phase Phase 2
Start date July 2009

See also
  Status Clinical Trial Phase
Active, not recruiting NCT05488626 - Daily Adaptive Radiation Therapy: An Individualized Approach for Stage III Lung Cancer N/A
Recruiting NCT02076282 - MRI Optimization Study in Stage III NSCLC N/A
Terminated NCT01577212 - Individualized Dose Prescription in Advanced Stage Lung Cancer Patients Using Modern (Chemo)Radiotherapy Phase 2
Withdrawn NCT01336543 - Consolidation Chemotherapy/Concurrent Chemo-radiotherapy for Inoperable Stage III Non-small Cell Lung Cancer (NSCLC) Phase 2
Completed NCT01102231 - Chemoradiotherapy in Stage III Non-small Cell Lung Cancer (NSCLC) Phase 2
Completed NCT00019006 - Vaccine Therapy in Treating Patients With Colon, Pancreatic, or Lung Cancer Phase 1
Recruiting NCT06082492 - The Beneficial Value of PET/CT in the Follow-up of Stage III Non-small Cell Lung Cancer Patients N/A
Active, not recruiting NCT03049618 - Recombinant EphB4-HSA Fusion Protein and Pembrolizumab, MK-3475 Phase 2
Recruiting NCT03077854 - Image-Guided Functional Lung Avoidance Thoracic Radiotherapy for Lung Cancer: A Single-Blind Randomized Trial N/A
Recruiting NCT05157542 - Neoadjuvant LDRT Combined With Durvalumab in Potentially Resectable Stage III NSCLC Phase 1
Recruiting NCT05361174 - A Study to Investigate the Efficacy and Safety of an Infusion of IOV-4001 in Adult Participants With Unresectable or Metastatic Melanoma or Stage III or IV Non-small-cell Lung Cancer Phase 1/Phase 2
Active, not recruiting NCT03048500 - Nivolumab and Metformin Hydrochloride in Treating Patients With Stage III-IV Non-small Cell Lung Cancer That Cannot Be Removed by Surgery Phase 2
Not yet recruiting NCT05891080 - Neoadjuvant Therapy With Toripalimab and JS004 Combined With Platinum-based Doublet Chemotherapy for Resectable or Potentially Resectable Stage III Non-small Cell Lung Cancer: A Randomised Controlled, Open-label, Phase 2 Trial Phase 2
Active, not recruiting NCT01948141 - Nintedanib in Treating Patients With Advanced Non-Small Cell Lung Cancer Who Have Failed Up to Two Previous Chemotherapy Regimens Phase 2
Completed NCT01282437 - Prophylactic Cranial Irradiation (PCI) vs Observation in Stage III NSCLC Phase 3
Recruiting NCT05631574 - Study of Covalent Menin Inhibitor BMF-219 in Adult Patients With KRAS Driven Non-Small Cell Lung Cancer, Pancreatic Cancer, and Colorectal Cancer Phase 1
Recruiting NCT05157503 - Treatment of Patients With Stage III Non-small Cell Lung Cancer in Russia"
Recruiting NCT05468242 - Study of Tislelizumab for Locally Advanced Non-Small Cell Lung Cancer Following Neoadjuvant Chemotherapy Plus Tislelizumab ± Bevacizumab and Definitive Concurrent Chemoradiation Therapy Phase 2
Active, not recruiting NCT06102057 - PACCELIO - FDG-PET Based Small Volume Accelerated Immuno Chemoradiotherapy in Locally Advanced NSCLC Phase 2
Recruiting NCT04984148 - Construction of CT Radiomics Model for Predicting the Efficacy of Immunotherapy in Patients With Stage III NSCLC