Examining B12 Deficiency Associated With C677T Mutation on MTHFR Gene in Terms of Commonness and Endothelial Function

B12 Deficiency Combined With C677T Mutation on MTHFR Gene Clinical Trial

Official title: Examining the Commonness of the C677T Mutation in the MTHFR Gene in Subjects With B12 Deficiency and the Influence of the B12 Deficiency Combined With the C677T Mutation on the MTHFR Gene on Endothelial Function.

Status Terminated

Clinical Trial Summary

The purpose of this study is to determine the commonness of the C677T mutation in the MTHFR gene in subjects with B12 deficiency. Also, we'd like to investigate the effect of B12 deficiency combined with the C677T mutation on endothelial function.

Clinical Trial Description

we showed that patiebts with B12 deficiency have higher than expected frequency of MTHFR mutation and patients with both abnormalities havean abnormal endothelial function ;

Study Design

Allocation: Non-Randomized, Endpoint Classification: Efficacy Study, Intervention Model: Parallel Assignment, Masking: Open Label, Primary Purpose: Screening

Related Conditions & MeSH terms

• B12 Deficiency Combined With C677T Mutation on MTHFR Gene

• NCT number: NCT00730574
• Study type: Interventional
• Source: Carmel Medical Center
• Status: Terminated
• Phase: N/A
• Start date: July 2008
• Completion date: January 2012