Clinical Trials Logo

Clinical Trial Summary

This study will investigate AQW051 in patients with either mild Alzheimer's disease or amnestic mild cognitive impairment. The effect on cognitive impairment will be measure using validated computerized tests which measure cognitive function. This study will also explore the safety and tolerability of AQW051 in these patients.


Clinical Trial Description

n/a


Study Design

Allocation: Randomized, Endpoint Classification: Safety/Efficacy Study, Intervention Model: Parallel Assignment, Masking: Double Blind (Subject, Investigator), Primary Purpose: Treatment


Related Conditions & MeSH terms


NCT number NCT00582855
Study type Interventional
Source Novartis
Contact
Status Terminated
Phase Phase 2
Start date December 2007

See also
  Status Clinical Trial Phase
Completed NCT01525368 - Outcome Predictors of a Cognitive Intervention in aMCI N/A
Completed NCT00785759 - Brain Uptake and Safety With Probable Alzheimer's Disease, Amnestic Mild Cognitive Impairment and Healthy Volunteers Phase 2
Recruiting NCT05903573 - Training Response Artificial Intelligence Network (TRAIN) N/A
Completed NCT02562989 - [18F]MK-6240 Positron Emission Tomography (PET) Tracer First-in-Human Validation Study (MK-6240-001) Phase 1
Completed NCT02910739 - An Open-Label Study Investigating MK-8931 in Participants With Mild and Moderate Hepatic Insufficiency (MK-8931-016) Phase 1
Not yet recruiting NCT04103463 - Interactive Stepping Exercise on Memory N/A
Completed NCT04185298 - mSIM: Mobile Simultaneous Aerobic Exercise and Memory Training Intervention for Amnestic Mild Cognitive Impairment N/A
Recruiting NCT04063956 - COG-REAGENT: COGnitive tRaining in patiEnts With Amnestic Mild coGnitive impairmENT N/A
Terminated NCT01953601 - Efficacy and Safety Trial of Verubecestat (MK-8931) in Participants With Prodromal Alzheimer's Disease (MK-8931-019) Phase 3
Recruiting NCT06041152 - Does Psilocybin Change Synaptic Density in Amnestic Mild Cognitive Impairment Phase 2
Completed NCT01962038 - A Combined Training Program for Veterans With Amnestic Mild Cognitive Impairment N/A
Recruiting NCT06444568 - Modified Ketogenic Diet in Amnestic Mild Cognitive Impairments N/A
Recruiting NCT03133052 - CTA-MCI: Cognitive Control Training in Patients With Amnestic Mild Cognitive Impairment(CTA-MCI) N/A
Not yet recruiting NCT05987007 - Sleep Interventions and Neurocognitive Outcomes N/A
Recruiting NCT04240561 - Characterizing Variability in Hearing Aid Outcomes in Among Older Adults With Alzheimer's Dementia N/A
Completed NCT01767909 - The Study of Nasal Insulin in the Fight Against Forgetfulness (SNIFF) Phase 2/Phase 3
Terminated NCT01072812 - Study of the Pharmacokinetics and Pharmacodynamics of POSIPHEN® in Subjects With Amnestic Mild Cognitive Impairment Phase 1
Completed NCT00643266 - Recollection Training in Healthy Older Adults and Older Adults With Amnestic Mild Cognitive Impairment N/A
Active, not recruiting NCT04504630 - Noninvasive Brain Stimulation on Memory in Individuals With Mild Cognitive Impairment and History of Brain Injury N/A
Recruiting NCT05446584 - Pathways Relating Amnestic MCI to a Mild Traumatic Brain Injury History Phase 2