Diabetes Mellitus Clinical Trial
Official title:
Corneal Endothelial Cell Loss in Diabetes Type II During Cataract Surgery
The aim of the present study is to evaluate changes in the morphology and function of the corneal endothelium before and after cataract surgery in patients with diabetes type II. Also to explain if determination of HgbA1c in diabetics is a predictor for the changes in morphology and function.
Thirty patients with Diabetes type II and thirty non-diabetes patients scheduled to cataract
surgery (phacoemulsification with intraocular lens implantation) were invited to participate
in the study. Preoperatively, all patients had a full eye examination and 3 endothelial cell
photos were taken.
Three months postoperatively the patients were called for a re-examination including 3
endothelial cell photos. The function of the cornea is dependent of the number and
morphology of the endothelial cells, and even small traumas like cataract surgery may
disrupt the cornea integrity leading to corneal haze and blur. Diabetics may be more
vulnerable to corneal stress.
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Observational Model: Case-Only, Time Perspective: Prospective
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