Treatment of Severe Hypertension During Pre-Eclampsia: A Preliminary Equivalence Study Between Urapidil and Nicardipine

Hypertension During Pre-Eclampsia Clinical Trial

Official title: Treatment of Severe Hypertension During Pre-Eclampsia.A Preliminary Equivalence Study Between URAPIDIL and NICARDIPINE

Status Recruiting

Clinical Trial Summary

The aim of this study is to confirm that URAPIDIL is as efficient and as safe as NICARDIPINE to correct severe hypertension in pre-eclamptic patients.

• efficacy endpoint : mean arterial blood pressure corrected to 105-125 mmHg after 120 min of study drug administration.

• safety endpoints : clinical, biological and ultrasound observation for any side effect.All infants will be observed in the neonatology unit (during 48h).

Clinical Trial Description

n/a

Study Design

Allocation: Randomized, Endpoint Classification: Safety/Efficacy Study, Intervention Model: Parallel Assignment, Masking: Open Label, Primary Purpose: Treatment

Related Conditions & MeSH terms

• Eclampsia
• Hypertension
• Hypertension During Pre-Eclampsia
• Pre-Eclampsia

• NCT number: NCT00409253
• Study type: Interventional
• Source: University Hospital, Strasbourg, France
• Contact: Pierre Auguste DIEMUNSCH, MD
• Phone: 33.3.88.12.70.78
• Email: Pierre.Diemunsch@chru-strasbourg.fr
• Status: Recruiting
• Phase: Phase 3
• Start date: June 2007
• Completion date: August 2010