Twinrix Alternative Schedule Study

Antibody Response After Vaccination Clinical Trial

Official title: A Study Comparing the Effectiveness of Two Different Vaccination Schedules of the Combined Hepatitis A and B Vaccine(Twinrix Adult1440/20)

Status Active, not recruiting

Clinical Trial Summary

To compare the efficiency of protection against hepatitis-B virus by administration of the combined vaccine against hepatitis A and B using the schedule 0-1-12 months against the schedule 0-1-6 months.

1. To compare the seroconversion (>= 1 IU/l) and seroprotection (>= 10 IU/l) rate at month 6,7,12 and 13.

2. To compare the distribution of anti-HBs at these different moments.

Clinical Trial Description

n/a

Study Design

Allocation: Randomized, Endpoint Classification: Bio-equivalence Study, Intervention Model: Parallel Assignment, Masking: Open Label, Primary Purpose: Prevention

Related Conditions & MeSH terms

• Antibody Response After Vaccination

• NCT number: NCT00216229
• Study type: Interventional
• Source: IDEWE Occupational Health Services
• Status: Active, not recruiting
• Phase: Phase 4
• Start date: September 2004
• Completion date: February 2006