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Lung Open Ventilation to Decrease Mortality in the Acute Respiratory Distress Syndrome — LOVS  

Acute Respiratory Distress Syndrome Clinical Trial

Official title:
A Randomized Trial of a Lung-Open Ventilation Strategy in Acute Lung Injury

Clinical Trial Summary

A multinational, randomized trial comparing two lung protecting strategies of respiratory life support among critically ill patients with severe lung injury.

Clinical Trial Description

To compare an innovative Lung Open Ventilation strategy with a proven low tidal volume strategy, hypothesizing that the Lung Open Ventilation strategy may reduce mortality, other organ dysfunction, and the duration of mechanical ventilation, intensive care, and hospital stay. ;

Study Design

Allocation: Randomized, Endpoint Classification: Efficacy Study, Intervention Model: Parallel Assignment, Masking: Open Label, Primary Purpose: Treatment

Related Conditions & MeSH terms

  • Acute Lung Injury
  • Acute Respiratory Distress Syndrome
  • Respiratory Distress Syndrome, Adult
  • Respiratory Distress Syndrome, Newborn
Clinical Trial Details
NCT number NCT00182195
Study type Interventional
Source McMaster University
Contact
Status Completed
Phase Phase 3
Start date August 2000
Completion date March 2006
View Details
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