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NCT ID: NCT05446493 Completed - Clinical trials for Erectile Dysfunction

Serum YKL-40 Level and Platelets Indices Among Patients With Diabetic Erectile Dysfunction

Start date: April 1, 2019
Phase: Phase 4
Study type: Interventional

The aim of this current study is to estimate serum level of YKL-40, serum total testosterone and platelets indices in diabetic patients with erectile dysfunction treated by daily tadalafil 5mg for 3 months.

NCT ID: NCT05444868 Completed - Clinical trials for Amputation; Traumatic, Limb, Lower

Validity and Reliability Study of Glittre Activities Of Daily Living Test in Amputees

Start date: July 15, 2022
Phase:
Study type: Observational

Glittre activities of daily living test is used in different populations. The test, which is valid and reliable in different populations, has not been validated in amputees. In our study, we wanted to investigate the validity and reliability of the Glittre activities of daily living test (Glittre ADL) test in amputees using a lower extremity prosthesis.

NCT ID: NCT05443763 Completed - Clinical trials for Children With Neurodevelopmental Disorders

Exploring the Experiences and Outcomes of a Summer Intensive Therapy Program- Mixed Methods Study

Start date: May 23, 2022
Phase: N/A
Study type: Interventional

The purpose of this study is to assess the effectiveness of an interdisciplinary intensive therapy program for ambulatory and non-ambulatory children with neurodevelopmental disorders across the ICF and to explore caregiver experiences and perspectives of the program.

NCT ID: NCT05442814 Completed - Postoperative Pain Clinical Trials

Anterior and Posterior Approaches of Suprascapular Nerve Block

Start date: March 15, 2022
Phase: N/A
Study type: Interventional

Suprascapular nerve is a mixed motor and sensory peripheral nerve arising from the superior trunk of brachial plexus.The suprascapular nerve runs through the posterior triangle of the neck, anterior of the trapezius muscle and dorsal of the omohyoid muscle, in direction of the scapula. Suprascapular nerve block is performed by anterior and posterior approach. Posterior approach of the suprascapular nerve block has been shown for many years to provide effective analgesia in the shoulder region for the chronic and acute pain. There are studies showing that suprascapular block with anterior approach provides effective analgesia in shoulder arthroscopy. The aim of our study was to compare anterior and posterior approaches of suprascapular nerve block in terms of analgesic efficacy and patient safety.

NCT ID: NCT05441904 Completed - Clinical trials for NASH - Nonalcoholic Steatohepatitis

Study to Assess the Safety, Tolerability, and Pharmacokinetics of PXL770 in Healthy Subjects.

Start date: March 8, 2021
Phase: Phase 1
Study type: Interventional

The study was planned in 2 parts: Parts A and B. In Part A, we tested 2 single doses of the study medicine in healthy volunteers: 500 mg and 750 mg. Part B was an optional part to test once-daily doses of the study medicine in healthy volunteers. We aimed to assess the safety, tolerability find out the side effects and blood levels of the PXL770.

NCT ID: NCT05441891 Completed - Clinical trials for Asymmetric Sensorineural Hearing Loss

Effect of Modulated Auditory Stimulation on Interaural Auditory Perception

Start date: June 17, 2022
Phase: N/A
Study type: Interventional

This study analyzes the effect of an equalizer-modulated auditory intervention on the asymmetry of interaural auditory perception in groups with different emotional states such as well-being, anxiety, depression and mixed anxiety-depression.

NCT ID: NCT05440669 Completed - Clinical trials for Nasal Continuous Positive Airway Pressure

White Noise in Nasal Cpap Application

Start date: June 19, 2022
Phase: N/A
Study type: Interventional

The aim of this study is to determine the effect of white noise application on the pain and stress level of newborns receiving oxygen support via nasal CPAP in the Neonatal Intensive Care Unit. The research is a randomized controlled trial. The population of the study will be infants aged 0-28 days who were hospitalized for treatment in Şanlıurfa Training and Research Hospital between July and December 2022. The research sample; Babies of families who are hospitalized in the Neonatal Intensive Care Unit on the specified dates and meet the research criteria and volunteer to participate in the research will be formed. "Survey Form", "Follow-up Form" and "ALPS Neo Neonatal Pain and Stress Assessment Scale", White Noise, MP 3 Player, and Sound Decibel Measuring Device will be used to collect data.

NCT ID: NCT05438693 Completed - Clinical trials for Multiple Sclerosis, Relapsing-Remitting

Delayed Diagnosis of Multiple Sclerosis, Treatment Initiation and Non-adherence in Upper Egypt

Start date: June 1, 2020
Phase:
Study type: Observational

The earlier that MS can be diagnosed; the sooner treatment can be initiated with timely reduction of subclinical disease activity and prevention of disability progression. However, significant delays can still occur between noticing the first symptoms and receiving a diagnosis even before a person with symptoms suggestive of MS sees a neurologist. Such delays could be due to heterogeneity of clinical and imaging manifestations, which not only differ between patients, but also vary in individual patients over time. Moreover, lack of awareness of the primary care physicians about MS presentations, the limited accessibility to specialized centers or the non-availability of diagnostic tools such as MRI scanners and lumbar puncture, may further add to this delay and increases the risk of disability. There are also many factors that can contribute to delayed initiation of DMT after diagnosis like inadequate knowledge with DMT, their high coast and limited access to health care insurance services. Like many chronic conditions, non- Adherence to drug therapies is estimated up to 50%, with associated increased morbidity, mortality, and health care costs. To the best of our knowledge, this is the first study in upper Egypt that tries to address these factors. By conducting this study, we aim at identifying factors leading to delayed diagnosis of MS, initiation and adherence to DMT in order to translate recent advances in the diagnosis and treatment of MS into improved outcomes in the lives of people with MS and their families and to avoid many of the long-term economic and personal costs that result from unnecessary irreversible disability.

NCT ID: NCT05436288 Completed - Clinical trials for Persistent Corneal Epithelial Defect

A Study of the KIO-201 (Ocular Bandage Gel) for Improving Persistent Corneal Epithelial Defects

Start date: July 1, 2022
Phase: Phase 2
Study type: Interventional

The objective of this study is to evaluate the safety and effectiveness of topical KIO-201 in patients with persistent corneal epithelial defects (PED). KIO-201 will be administered six (6) times per day while awake for 4 weeks. The primary exploratory effectiveness outcome for this study is the percentage of patients achieving corneal healing as determined by corneal fluorescein staining and photos. The effectiveness endpoint will be evaluated by a reader using digital photography of fluorescein stained slit lamp photos and image analysis.

NCT ID: NCT05433870 Completed - Clinical trials for Posterior Reversible Encephalopathy Syndrome

Inflammatory Biomarkers for the Diagnosis of oPRES

Start date: July 1, 2022
Phase:
Study type: Observational

The purpose of this study is to explore the inflammatory biomarkers for the diagnosis of obstetric posterior reversible encephalopathy syndrome.