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NCT ID: NCT03405363 Completed - Clinical trials for Pulmonary Disease, Chronic Obstructive

Cardiovascular Events in Chronic Obstructive Pulmonary Disease Patients Initiating Olodaterol or Other Long-acting beta2 Agonists

Start date: January 31, 2018
Phase:
Study type: Observational

Examine the risk of cardiovascular events (cardiac arrhythmia or myocardial ischemia) or all-cause mortality in Chronic Obstructive Pulmonary Disease (COPD) patients who are new users of Olodaterol or other LABAs available for the treatment of COPD.

NCT ID: NCT03405168 Completed - Clinical trials for Advanced Breast Cancer

Routine Therapy Plus Moxifloxacin in Advanced Breast Cancer

Start date: January 1, 2018
Phase: Phase 2
Study type: Interventional

This is a phase II,single center,prospective, single arm clinical trial. The objective is to evaluate the efficacy and safety of routine therapy plus moxifloxacin in Advanced Breast Cancer whose evaluation is stable disease with a trend of progression.

NCT ID: NCT03405142 Completed - Clinical trials for Head and Neck Cancer

Panitumumab-IRDye800 Compared to Sentinel Node Biopsy and (Selective) Neck Dissection in Identifying Metastatic Lymph Nodes in Patients With Head&Neck Cancer

Start date: August 1, 2019
Phase: Phase 2
Study type: Interventional

This phase 2 trial studies how well panitumumab-IRDye800 works in identifying head and neck cancer that has spread to the lymph nodes in patients with head and neck cancer. Panitumumab-IRDye800 may help surgeons to identify metastatic lymph nodes during surgical removal of the primary tumor and/or lymph nodes of the neck with equal or better accuracy than the current methods.

NCT ID: NCT03405064 Completed - Clinical trials for Acute Bacterial Skin and Skin Structure Infections

Comparative Study of Levonadifloxacin (IV and Oral) With Linezolid (IV and Oral) in Acute Bacterial Skin and Skin Structure Infections (ABSSSI)

Start date: August 25, 2017
Phase: Phase 3
Study type: Interventional

This is a phase III, multi-center, randomized, active-comparator, study in subjects with ABSSSI. The study has two subgroups for assessment of efficacy and safety - oral subgroup 1 and IV subgroup 2. Each subgroup will comprise of two treatment arms.

NCT ID: NCT03405025 Completed - Clinical trials for Primary Hyperaldosteronism

Radiofrequency Endoscopic Ablation With Ultrasound Guidance: a Non-surgical Treatment for Aldosterone-producing Adenomas

FABULAS
Start date: February 21, 2018
Phase: N/A
Study type: Interventional

High blood pressure (hypertension) causes strokes and heart attacks. While most patients need long-term treatment with pills, some have a cause which can be removed, curing the hypertension. The commonest curable cause is a benign nodule in one of the hormone glands, the adrenals. About one in 20 patients have such a nodule, but difficulties with diagnosis, and reluctance to proceed to surgery for a benign condition, limit the number having adrenal gland surgery to fewer than 300 per year in the UK. A potential, and exciting, solution to this dilemma is to use a momentary electric current to cauterise the nodule (radiofrequency ablation), without affecting the rest of the adrenal gland, and avoiding the need for surgery. Nodules in the left adrenal gland are easily reached under mild sedation using a similar procedure as is standard for investigating stomach ulcers (endoscopy). The study is designed to show that this approach (endoscopic ultrasound guided radiofrequency ablation) is very safe, and to provide initial evidence that the hormone abnormality is cured.

NCT ID: NCT03404947 Completed - Clinical trials for Exercise Metabolism Following Ethanol Ingestion

Substrate Metabolism During Exercise Following Ingestion of Ethanol

Start date: November 13, 2017
Phase: N/A
Study type: Interventional

This study will investigate how ethanol (pure alcohol) influences carbohydrate and fat metabolism during prolonged, moderate intensity exercise. Participants will perform two bouts of cycling exercise with or without prior ingestion of ethanol, in a randomised order, separated by one week.

NCT ID: NCT03404921 Completed - Clinical trials for Esophageal Superficial Mucosal Lesion

Efficacy and Safety of Endoscopic Submucosal Tunnel Dissection for Superficial Esophageal Squamous Cell Carcinoma

Start date: January 1, 2018
Phase: N/A
Study type: Interventional

To evaluate the efficacy and safety profile of endoscopic submucosal tunnel dissection for superficial esophageal squamous cell carcinoma.

NCT ID: NCT03404622 Completed - Clinical trials for Mechanical Complication of Intrauterine Device

Immediate Post-placental Insertion of IUCD During Cesarean Delivery Versus 6 Week Post-Cesarean Insertion

Start date: September 20, 2016
Phase: Phase 1
Study type: Interventional

The aim of current study is to compare the rates of IUCD expulsion and complications in immediate post-placental insertion versus delayed IUCD insertion (6-weeks after cesarean delivery)

NCT ID: NCT03404323 Completed - Cataract Clinical Trials

"Cataract Surgery in Eyes With Epiretinal Membrane"

Start date: July 1, 2015
Phase: N/A
Study type: Observational

The purpose of the study is to evaluate retinal thickness change and the occurrence of central structural retinal changes after uneventful small-incision cataract surgery in eyes with asymptomatic early stages of epiretinal membrane.

NCT ID: NCT03403972 Completed - Clinical trials for Simvastatin Pharmacokinetics and Gut Microbiome

Evaluate the Effects of the Environmental Change in Intestine by Antibiotics on the Pharmacokinetic Characteristics of Simvastatin in Healthy Male Volunteers

Start date: December 6, 2017
Phase: Phase 1
Study type: Interventional

This phase 1 clinical trial is to evaluate the effects of the environmental change in intestine by antibiotics on the pharmacokinetic characteristics of simvastatin in healthy male volunteers. For change of intestine environment, especially the gut microbiota, investigators will administer PO vancomycin for 7 days, tid.