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Filter by:This study will be a randomised controlled trial examining whether a new type of needle free access device(TEGO) is associated with less episodes of infection of dialysis lines, when compared to the current gold standard. The investigators hypothesise that there will be less handling of the dialysis line by nursing staff and thus this will lead to lower rates of infection. The investigators will also assess whether these access devices lead to alterations in catheter blood flow rates when compared to the current gold standard.
The purpose of this study is to see if memantine is helpful in managing problematic symptoms in adults with autism, Asperger's disorder, or Pervasive Developmental Disorder NOS.
The primary end point is to evaluate the time to progression after gemcitabine alone versus Gemcitabine-based combination induction chemotherapy followed by concurrent chemoradiotherapy in locally advanced pancreatic cancer. The secondary end points are to evaluate the disease control rate, overall survival time, toxicity profile and compliance after induction chemotherapy and concurrent chemoradiotherapy as well as the disease control rate after inductional chemotherapy alone in locally advanced pancreatic cancer. Translational research including pharmacogenomic study and biomarker study will also be done concomitantly.
All newborn from the period 12.1988 to 31.12.2006 During the two last decades, hip ultrasound has gained acceptance as an accurate screening test for developmental dysplasia of the hip (DDH) and for monitoring the development and treatment of the condition. Debate continues over whether DDH that is detected by ultrasonography is necessarily clinically relevant. The diagnostic accuracy of ultrasound imaging for DDH in the screening population has not been investigated adequately. Studies that investigate the natural course of the disorder, the optimal treatment for DDH, and the best strategy for ultrasound screening are needed. Ultrasound screening at birth for DDH in all newborn infants is standard practice in some European countries but not in the United Kingdom, the United States, or Scandinavia. Evidence is insufficient to support or reject general ultrasound screening of newborns for DDH. (N.F.Woolacott etc 2006, systematic review BMJ) At Vestre Viken HF, Kongsberg, Norway, the investigators implemented universal ultrasound screening in 1998. We will present the long term outcome, including radiographs of the hips after 5-12 years.
Observations in patients with growth hormone (GH)-disturbances have suggested that GH/IGF-I might have anti-inflammatory effects. To elucidate this hypothesis the investigators have planned a study to investigate if 3 weeks administration of GH and subsequently the GH antagonist Pegvisomant (or vice versa) influence serum levels of different inflammatory markers in healthy volunteers.
The purpose of this study is to determine whether silver alginate (Algidex) patch is effective in the prevention of central line infections in very low birth weight infants.
The hypotheses that will be studied are: H0: Providers trained by a web based application for skill competency in basic life support (BLS) and automated external defibrillation (AED) are as competent as those who were trained by certified instructors using the European Resuscitation Council (ERC) curriculum H00-1: Providers who trained themselves with the used of web based training are more competent when they had a personal manikin for home exercise compared to providers who trained themselves with only a web based training H0-2: Providers who did not receive any training will score lower than those who did. Research questions for this study are: 1. What are the results in skill competency for non trained people? 2. What are the results in skill competency for trained people immediately after training? 3. What is the retention of skills for trained and non trained people after six months?
This study is a prospective, randomized trial that compares the effectiveness and retention of four different training methods for the use of an AED: A. Traditional instructor based learning; B. The use of a personal manikin with a DVD training to practice the necessary AED skills; C. The use of a personal manikin with a DVD training to practice the necessary AED skills and additional scenario training; D. Watching a 2.5 minutes DVD which shows the use of an AED. It is hypnotised that there are no differences between these training methods, in which case method D is most efficient to reach large number of people to learn BLS/AED skills. There are two interesting target groups to reach: 1. Younger people, as they might give the highest interest after training, as they normally live longer. 2. Older people as they are member of the most important group in risk and have therefore a higher change of being a witness of cardiac arrest. As there might be differences in the results between different training methods than can be related to age, each training group is distinguished to three different groups: 1. 21 years of younger; 2. between 21 and 50 years; 3. older than 50 years. It is hypnotised that there are no differences between younger and older students within each of the four training methods.
The purpose of this study is to determine if educational intervention is effective in reducing exacerbations of chronic obstructive pulmonary disease in patients with low-risk disease.
The aim of this research project is to establish a students' perspective to most medical schools in Taiwan. We expect that these surveys will provide helpful information to candidates for selection of medical school before admission, and will also be a useful reference guide to improve quality of medical education to our governmental policy makers.