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NCT ID: NCT03756415 Not yet recruiting - Clinical trials for Acute Hypercapnic Respiratory Failure

CO2 Clearance During Noninvasive Ventilation (NIV)

Start date: January 1, 2019
Phase: N/A
Study type: Interventional

In this randomized cross over study the investigators will evaluate the effects on gas exchange and patients' tolerance of a new CO2 non rebreathing devices incorporated in the mask vs the traditional mask COPD patients undergoing NIV for an episode of Acute Hypercapnia Respiratory Failure, will be randomized after at least 12 hour of ventilation to 1 h.trial with the usual full face mask or the same mask with the addition of a new CO2 clearance device

NCT ID: NCT03755115 Not yet recruiting - Clinical trials for Small Cell Lung Cancer Extensive Stage

SHR-1210 Combined With Epirubicin in the Treatment of Extensive Disease Small Cell Lung Cancer

Start date: February 1, 2019
Phase: Phase 2
Study type: Interventional

Patients with extensive disease SCLC after failure of first-line treatment were enrolled with SHR-1210 and epirubicin for 3 cycles to evaluate initial efficacy

NCT ID: NCT03753269 Not yet recruiting - Clinical trials for ST Segment Elevation Myocardial Infarction

Early Intracoronary Administration of Fasudil in the Primary PCI of ST-segment-Elevation Myocardial Infarction

Start date: July 1, 2019
Phase: Phase 4
Study type: Interventional

The study aims to evaluate whether an early intracoronary administration of Fasudil Hydrochloride during primary PCI of STEMI can improve epicardial and myocardial perfusion as well as clinical outcomes.

NCT ID: NCT03752931 Not yet recruiting - Clinical trials for Postoperative Cardiac Complication

Celiprolol Versus Ditiazem for the Prevention of Postoperative Cardiac Arrythmias in Thoracic Surgery

CelDilPreCA
Start date: December 2018
Phase: Phase 2
Study type: Interventional

Cardiac arrythmias are the most common cardiac complications after thoracic surgery. They are made primarily of postoperative atrial fibrillation (POAF). They are associated with an increased risk of stroke, increased length of hospital stay and cost of care, and increased long-term mortality. Randomized , single-blind prospective study in the anesthesia and intensive care department of Abderrahmen Mami hospital Ariana Tunisia comparing the efficacy of Diltiazem versus Celiprolol in the prevention of postoperative cardiac arrythmias in patients proposed for pneumonectomy and bilobectomy.

NCT ID: NCT03752476 Not yet recruiting - Clinical trials for Antibiotic Resistant Infection

Impact of Number of Rank of B-lactam Antibiotics on Emergence on Multidrug Resistant Bacteria

INOR Blact
Start date: January 1, 2019
Phase:
Study type: Observational

This study evaluates the impact of rank of Beta lactam antibiotics on emergence of mutlidrug resistant bacteria colonization in intensive care It's retrospective case controle study. Cases are colonized patient by multidrug resistant bacteria hospitalized in intensive care during the fist hospitalization in intensive care. Temoin are patients with the same characteristics than case but no colonized by multidrug resistant bacteria.

NCT ID: NCT03751748 Not yet recruiting - Clinical trials for Heart Failure With Normal Ejection Fraction

Flow Regulation by Opening the Septum in Patients With Heart Failure Trial

FROST-HF
Start date: January 1, 2019
Phase: N/A
Study type: Interventional

To investigate the safety and efficacy of a novel atrial flow regulator (AFR) device in patients with heart failure and preserved ejection fraction.

NCT ID: NCT03748615 Not yet recruiting - Edentulous Patients Clinical Trials

The Efficiency of Computer Guided Ridge Splitting Using Piezosurgery in Horizontally Deficient Posterior Mandible

Start date: November 20, 2018
Phase: N/A
Study type: Interventional

The use of implants has significantly increased prosthetic options for edentulous patient. However, implant placement in the Posterior mandibular region is often hampered significantly by insufficient atrophic width limitations

NCT ID: NCT03748147 Not yet recruiting - Clinical trials for Induction of Labor Affected Fetus / Newborn

Cervical Ripening in Obese Women: Efficacy of 25 mcg Versus 50 mcg of Misoprostol

Start date: December 10, 2018
Phase: N/A
Study type: Interventional

This is a prospective clinical trial to determine if 50 mcg versus 25 mcg po every four hours of misoprostol has improved efficacy and similar safety in obese women undergoing cesarean section.

NCT ID: NCT03744208 Not yet recruiting - Clinical trials for Head and Neck Squamous Cell Carcinoma

SCT200 Injection in Patients With Head and Neck Squamous Cell Carcinoma

Start date: December 30, 2018
Phase: Phase 2
Study type: Interventional

The purpose of this study is to evaluate the efficacy and safety of first-line with recombinant anti-EGFR monoclonal antibody(SCT200)and standard chemotherapy in patients with Recurrent and/or Metastatic Head and Neck Squamous Cell Carcinoma.

NCT ID: NCT03742115 Not yet recruiting - Clinical trials for Hemophagocytic Lymphohistiocytosis

Etoposide in the First-line Treatment of Adult EBV-HLH

Start date: December 1, 2018
Phase: Phase 3
Study type: Interventional

his study aimed to investigate the efficacy of etoposide as the first line therapy for adult Epstein-Barr virus-associated hemophagocytic lymphohistiocytosis.