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NCT ID: NCT04739657 Completed - Clinical trials for Coronary Artery Disease

Clinical Evaluation of A New High-speed and High-resolution Intravascular Ultrasound System

NEW-IVUS
Start date: March 1, 2021
Phase:
Study type: Observational

Insight Lifetech Intravascular Ultrasound Diagnostic System (referred to as Insight Lifetech IVUS system below),is a new high-speed and high-resolution device for clearly defining vessel architecture and plaque morphology, providing quantitative and qualitative assessment of coronary arteries. Besides, IVUS has already an established role in guidance and optimization of percutaneous coronary intervention. This study will compare the differences, if any, between the intravascular ultrasound(IVUS) results measured by the two different IVUS diagnostic systems.

NCT ID: NCT04739241 Completed - Clinical trials for Type 2 Diabetes Treated With Insulin

Premixed vs Basal Bolus Insulin Therapy in Older Patients With Type 2 Diabetes

Start date: January 24, 2014
Phase: Phase 4
Study type: Interventional

The purpose of this study is to compare efficacy and security of premixed insulin treatment vs basal bolus insulin treatment in older patients with poorly controlled type 2 diabetes.

NCT ID: NCT04739176 Completed - Clinical trials for Functional Neurological Symptom Disorder

Mirror Therapy Rehabilitation for Motor Functional Neurological Disorders.

FND-mirror
Start date: March 9, 2021
Phase: N/A
Study type: Interventional

Motor functional neurological disorders (FND) correspond to motor symptoms that are unexplained by an organic lesion but are due to cerebral dysfunction. Patients with these disorders have high rates of disability and health care utilization, and their quality of life is as impaired as that of patients with an "organic" disease. Accompanying these patients in their often-complex health journey represents a socio-economic and human challenge that demands interdisciplinary collaboration. Rehabilitation is seen as an important part of the therapy for motor FND. However, further research is needed to refine appropriate interventions and to create evidence-based recommendations. In this study, patients suffering from a functional neurological motor disorder of the upper limb will be included in a novel rehabilitation protocol that includes computerized mirror therapy. The study will used a multiple baseline, across subjects, single-case experimental design (SCED). In this type of design, each subject is his own control, with individual parameters being repeatedly measured in the presence and absence of the intervention of interest (computerized mirror therapy). Computerized mirror therapy could restore the coherence between the motor program and its execution. The investigators hypothesize that this process could re-normalize upper-limb motor activity and that this will have a beneficial impact on manual dexterity, quality of life, and mental representation capacities of the upper limb. The objective of this project is to use the single case experimental design method to investigate the efficacy of rehabilitation with computerized mirror therapy for patients suffering from motor neurological disorders (FND) of the upper limb.

NCT ID: NCT04738903 Completed - Clinical trials for Patients With Myopic Spherical Equivalent up to -12 Diopters

Q Value Customized Versus Wavefront Optimized Ablation in Femtosecond Laser-Assisted LASIK

Start date: June 1, 2020
Phase: N/A
Study type: Interventional

Corneal asphericity is expressed numerically as the "Q-value". A minus value means that corneal curvature flattens towards the periphery and the cornea is prolate in shape, but when the curvature steepens towards the periphery, the cornea is oblate in shape and has a positive Q-value. The current study evaluates the effect of LASIK eye surgery on corneal asphericity by comparing 2 software treatment platforms; the Q value customized ablation versus the conventional Wave-front optimized ablation in a fellow eye study pattern.

NCT ID: NCT04738890 Completed - Clinical trials for The Quality of Life of Parents of Children With Food Allergy

Online Mindfulness-based Cognitive Therapy for Parents of Children With Food Allergies

Start date: March 2, 2021
Phase: N/A
Study type: Interventional

This study aims to conduct an initial evaluation of adapted, live online, mindfulness-based cognitive therapy for parents and carers of children with food allergies (MBCT-PCCFA).

NCT ID: NCT04738682 Completed - Clinical trials for Patients in Rehabilitation

Intervention of Diet Registration Method for Rehabilitation Patients

Start date: February 15, 2021
Phase: N/A
Study type: Interventional

Study aims to investigate whether dietary registration can be performed with greater precision using digital registration units (mobile devices), rather than conventional paper based dietary registers. Study intervention is based in the M3 rehabilitation unit, as part of Hobro hospital. The intervention will proceed until 6 full-day dietary registrations have been collected per patient (40 patients total), 3 for each registration method. The estimated time requirement is 30 days.

NCT ID: NCT04737902 Completed - Postoperative Pain Clinical Trials

ESP Block, CNP and QoL After VATS

Start date: January 1, 2019
Phase:
Study type: Observational

The Erector Spinae Plane Block (ESPB) is an adequate alternative for pain management after video-assisted thoracoscopy surgery (VATS). The incidence of postoperative chronic neuropathic pain (CNP) and the quality of life (QoL) in patients with ESPB after VATS remain unknown. We hypothesised that patients with ESPB would have a low incidence of acute and CNP and would report a good QoL up to three months after VATS.

NCT ID: NCT04737226 Completed - Mobility Limitation Clinical Trials

The Relation of Ankle Mobility and Achilles Tendon, Plantar Fascia and Iliotibial Band Mechanical Properties

Start date: December 12, 2020
Phase: N/A
Study type: Interventional

The myotonometric assessment is becoming popular and important in athletic population. It is mentioned an alternate method than expensive methods, and it is easy and reliable assessment. Still there is not enough information of mechanical characteristics in athletic population and ankle mobility. Most clinicians or trainers can use this results and technique for enhancing performance, rehabilitation or prevention

NCT ID: NCT04737187 Completed - Clinical trials for Refractory Metastatic Colorectal Cancer

Phase III Study of Trifluridine/Tipiracil With and Without Bevacizumab in Refractory Metastatic Colorectal Cancer Patients

SUNLIGHT
Start date: November 25, 2020
Phase: Phase 3
Study type: Interventional

This study is designed as an international, open-label, controlled two-arm, randomized phase III comparison study evaluating the efficacy and safety of trifluridine/tipiracil in combination with bevacizumab versus trifluridine/tipiracil monotherapy in patients with refractory mCRC.

NCT ID: NCT04737096 Completed - Dementia Clinical Trials

DAOIB Combined With tDCS for Early-phase Dementia

Start date: January 1, 2020
Phase: Phase 2
Study type: Interventional

This is a 24-week randomized, double-blind, placebo-controlled trial. We will enroll patients with aMCI or mild AD. All patients will receive 2 weeks of tDCS (5 sessions per week, 10 sessions in total) during the first 2 weeks of the study, and will also be allocated randomly to either of 2 treatment groups for 24 weeks: (1) DAOIB group; (2) placebo group. We will assess the patients every 8 weeks during the treatment period (weeks 0, 8, 16, and 24). We hypothesize that augmentation with DAOIB will yield better effect than tDCS alone in improving the cognitive function, global functioning and quality of life in patients with aMCI or mild AD.