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Osteoarthritis clinical trials

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NCT ID: NCT04242303 Completed - Knee Osteoarthritis Clinical Trials

Effectiveness of Inertial Sensors vs the Conventional Technique for the Execution of the Bone Resections in Primary TKA

Start date: September 18, 2019
Phase: N/A
Study type: Interventional

Comparison of surgical technique for the execution of bone resections in total knee arthroplasty. Used technique are: a non-invasive extramedullary technique (EM technique) based on the use of inertial sensors for cutting guides positioning and conventional technique (IM technique), based on the use on intramedullary stem. Our hypothesis is that the EM technique based on the use of inertial sensors leads to a reduction in the number of outliers equal to or greater than 20% compared to the outliers obtained with the conventional technique.

NCT ID: NCT04241978 Completed - Osteoarthritis Clinical Trials

Development and Evaluation of a Web Based Decision Aid for Patients With Hip Osteoarthritis

Start date: February 17, 2020
Phase: N/A
Study type: Interventional

The main goal of this study is assess the effectiveness of a PtDA for patients with hip osteoarthritis

NCT ID: NCT04238598 Completed - Knee Osteoarthritis Clinical Trials

Intra-articular Pulsed Radiofrequency Neuromodulation Versus Intra-articular Steroids for Painful Knee Osteoarthritis

Start date: October 8, 2019
Phase: N/A
Study type: Interventional

To compare the efficacy of intra-articular pulsed radiofrequency to intra-articular steroids in patients with moderate-severe painful osteoarthritis of the knee.

NCT ID: NCT04235972 Completed - Clinical trials for Osteoarthritis Wrist

Evaluation of Staple Watson Wrist Arthrodesis

ESWWA
Start date: August 3, 2020
Phase: N/A
Study type: Interventional

When the wrist is damaged, for traumatic or degenerative reasons, the cartilage is worn out and the bones rub together: this is osteoarthritis. In order to stop this pain, it may be necessary to block these bones from each other, sacrificing mobility to achieve indolence. Multiple techniques are described according to the type of osteoarthritis and for each type of osteoarthritis itself, but the principle remains the same. The methods currently commonly proposed are the staple and the screwed plate. The aim of the study is to evaluate the surgical practice of the Orthopaedics and Traumatology department of the University Hospital of Rennes, and its long-term results, as this type of surgery is intended to be definitive.

NCT ID: NCT04234685 Completed - Clinical trials for Osteoarthritis, Knee

Determining the Effectiveness of a New Phototherapy Treatment for the Knee Osteoarthritis

Start date: November 8, 2018
Phase: N/A
Study type: Interventional

Light therapy (phototherapy) has previously been shown to help reduce pain for people with musculoskeletal pain conditions, such as knee osteoarthritis (OA). A new phototherapy has been developed that allows for customizing the intensity of light based on patient characteristics, such as the patient size and skin type. This new phototherapy approach needs to be evaluated to determine its effects. This study has been planned to determine how effective the new phototherapy is, but first it needs to be determined whether the study plans are feasible. This study will determine the feasibility of the full study by pilot testing the methods for the full trial with a group of 20 people with knee osteoarthritis. Participants will be randomly assigned to either receive the new phototherapy approach or a placebo phototherapy twice/week for four weeks. Pain and function will be measured over the four week treatment period and 12-weeks follow-up.

NCT ID: NCT04231318 Completed - Clinical trials for Osteoarthritis, Knee

Study of Cingal® and Triamcinolone Hexacetonide for the Relief of Knee Osteoarthritis Pain

Start date: September 11, 2020
Phase: Phase 3
Study type: Interventional

This is a multi-center, randomized, double-blind, parallel group, placebo controlled trial to compare the safety and effectiveness of a single injection of Cingal® to a single injection of Triamcinolone Hexacetonide (TH) to achieve pain relief and other symptoms of osteoarthritis of the knee.

NCT ID: NCT04229394 Completed - Clinical trials for Osteoarthritis (OA) of the Knee

2ccPA Study in Patients With Symptomatic Knee Osteoarthritis

Start date: February 13, 2018
Phase: Phase 1
Study type: Interventional

This clinical trial is designed to determine safety and tolerability as well as the MTD of a single-dose 2ccPA and PK data in symptomatic knee OA.

NCT ID: NCT04229225 Completed - Knee Osteoarthritis Clinical Trials

A Study of Single and Repeat Dose Administration of UBX0101 in Patients With Osteoarthritis of the Knee

Start date: January 23, 2020
Phase: Phase 1
Study type: Interventional

A study to assess safety, tolerability and clinical effects of single and repeat dose intra-articular administration of UBX0101 in patients with moderate to severe painful knee osteoarthritis (OA).

NCT ID: NCT04227860 Completed - Knee Osteoarthritis Clinical Trials

Balance and Strength Exercise in Knee Osteoarthritis Patients

Start date: January 20, 2020
Phase: N/A
Study type: Interventional

The aim of this study is to assess the effect of balance exercise on dynamic balance and physical function in 80 patients with different grades of primary knee osteoarthritis (KOA).

NCT ID: NCT04225182 Completed - Gonarthrosis Clinical Trials

Evaluation of the Effectiveness of a Muscular Strengthening Protocol With an Instrumented Orthosis for Gonarthrosis Patients

Start date: January 22, 2020
Phase: N/A
Study type: Interventional

The management of knee osteoarthritis via a physical activity protocol for rehabilitation has convincing results. However, the effectiveness of these protocols could be improved with a connected instrumented knee brace with an exercise protocol adapted for the patient which is supervise by an online physiotherapist to check the progression during home-based rehabilitation.