View clinical trials related to Osteoarthritis, Knee.
Filter by:The purpose of this study is to obtain patient oriented and clinically oriented physical function outcomes both pre-operatively and post-operatively in patients receiving a total knee arthroplasty.
The main purpose of this study is to test if LY2951742 relieves mild to moderate knee pain. The study drugs will be given as an injection under the skin and as an oral capsule. The study will last about 28 weeks for each participant.
Physiotherapists' knee OA care is suboptimal. Exercise therapy including a combination of aerobic, muscle strengthening and functional exercises is not always performed and a lot of treatments are used for which there is no evidence. By a continuing education session and a pop-up in the electronic patient file, this study wants to improve knee OA care by focusing on combined exercise therapy. The study will be performed in collaboration with Pro-Q-Kine, an independent organization implementing quality improvement in Belgian physiotherapists' care. Besides Pro-Q-Kine the study will be performed in collaboration with two or three software producers of physiotherapists' electronic patient files that reached a national homologation for their respective software packages and covering a large part of the Flemish physiotherapists. Pro-Q-Kine will organize sessions of continuing education with a focus on optimal knee OA care. These sessions will be performed in LOK-groups (local peer-groups of physiotherapists who meet each other for continuing education). At these sessions the physiotherapists will be asked to take part to the study. A pop-up will be installed in the electronic patient file of the participating physiotherapists, lightening up when physiotherapists register a patient with knee OA. The pop-up includes a short message about optimal knee OA care. The physiotherapists will also receive a script for a query in their electronic patient files in order to extract those patients that initiated a treatment for knee OA between 1 year and 3 months before the therapists received education. These patients will receive a letter of their respective physiotherapists in which they are addressed to take part to the study. An informed consent, patient questionnaire and retour-envelope will be included. There will also be the opportunity to complete the questionnaire electronically with an electronic informed consent. The patient questionnaire will include some background details (such as age and gender) and details about the physiotherapeutic treatments they received for knee OA. The patient questionnaire will be coded with a number, referring to the physiotherapist and to the individual patient (the first patient of the first physiotherapist will be coded as 1.01, the 10th patient of the 14th physiotherapist will be coded as 14.10). Patients' names will not be revealed to the investigators and physiotherapists will not have any access to the completed patients' questionnaires. The general practitioners in the environment of the physiotherapist will (probably) receive a letter from the researchers. This letter will contain information about the importance of referral to a physiotherapist in knee OA care and about knee OA care in general. This letter will also refer to the study that is going on in physiotherapists' care, without details. Six months after the installation of the pop-up, the physiotherapists will be asked again to perform the query to extract patients out of the electronic patient file that have been treated for knee OA and whose treatment sessions had been started in the period of three months from the installation of the pop-up.
Evaluate Clinical Performance of Vanguard Knee with E1 Bearing in Korean Patient Population
The purpose of this study is to investigate whether there is quantitative motor-sparing of the quadriceps muscles following adductor canal nerve block versus femoral nerve block. Patients will be randomly placed into one of three treatment groups: 1) Femoral nerve block, 2) Adductor canal nerve block - low volume, or 3) Adductor canal nerve block - high volume. Quadriceps function will be assessed in the operating room using a skin patch and electrical stimulation. Follow up visits with the patients will continue over the course of 2 days during patient's stay at the hospital. A total of 60 patients will be enrolled for the study.
The purpose of this study is to obtain patient-oriented and clinically-oriented physical function outcomes both pre-operatively and post-operatively in patients receiving a total knee arthroplasty .
The purpose of this study is to evaluate the ability of a wearable therapeutic ultrasound device to reduce pain and increase mobility for subjects with knee osteoarthritis.
The purpose of this prospective data collection is to track patients who are treated at HSS who are confirmed with knee osteoarthritis. The registry will collect prospective patient related and functional outcomes (including use of assistive devices), medication use and imaging data on patients with confirmed osteoarthritis, and the effect of different medical interventions that include PRP, Synvisc / Orthovisc /Euflexxa, bracing, suggested exercises, supplements, and diet. Information from the data collection will be used to compare outcomes of non-surgical alternatives with the end point being knee arthroplasty. The information results will enhance our knowledge of the long-term efficacy and effectiveness of non-surgical interventions intended to treat the progression of osteoarthritis. Hypotheses: - Different non-surgical interventions such as PRP, Synvisc®, Orthrovisc®, Euflexxa, bracing, physical therapy, and a prescribed combination of exercise, diet, and supplements will demonstrate statistically significant differences in patient pain and functional outcomes compared to usual interventions including use of NSAIDs, corticosteroid injections, and use of assistive devices such as canes. - Non-operative interventions for knee osteoarthritis will be associated with different rates of breakdown of articular cartilage and different rates of progression of osteoarthritis as evidenced by MRI or joint space narrowing on standing knee films? - Education about available non-operative treatment methods may change time the end point of total or partial knee replacement for patients with knee osteoarthritis of varying severity. - Different non-operative interventions will be associated with different times to total or partial knee arthroplasty in patient with knee osteoarthritis of similar severity. - An electronic data capture system (EDC) for osteoarthritis patients will improve patient care and patient outcomes.
This study is looking at whether virtual reality combined with pain coping skills training helps reduce pain in people who suffer from OA of the knee. Eligible participants will be asked to come into the study offices for one visit where they will fill out a couple of questionnaires, do some low impact performance tasks and be taught pain coping skills while looking into a 3D virtual reality viewer.
This study is designed to monitor long term clinical outcomes of the iUni G2+ unicompartmental knee replacement