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Osteoarthritis, Knee clinical trials

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NCT ID: NCT05287802 Completed - Knee Osteoarthritis Clinical Trials

The Efficacy of Balance and Proprioception Exercises in Patients With Knee Osteoarthritis

Start date: May 2014
Phase: N/A
Study type: Interventional

This study aime to investigate the effects of balance and proprioception exercises using two different methods (classical balance training and Balance Systemâ„¢ SD) in addition to strengthening exercises on dynamic balance, pain, functional status and quality of life in patients with knee osteoarthritis (OA).

NCT ID: NCT05286775 Recruiting - Clinical trials for Osteoarthritis, Knee

Knee Osteoarthritis Disabling Pain Program for the Brazilian Unified Health System

Start date: March 15, 2022
Phase: N/A
Study type: Interventional

This is a Randomized Clinical Trial to compare two interventions for reducing knee pain and improving knee function of patients with knee osteoarthritis. Sixty participants will be randomly allocated to one of the intervention groups, either a knee educational program or a combination of knee educational program and medical interventions. Participants will be assessed primarily on function and pain, as well as other secondary outcomes at baseline, at the end of the interventions, and three months after the end of the interventions.

NCT ID: NCT05283889 Recruiting - Clinical trials for Osteoarthritis, Knee

Genicular Radiofrequency Ablation Following Total Knee Arthroplasty

GRATKA
Start date: May 11, 2022
Phase: N/A
Study type: Interventional

Currently, nearly 1 million total knee arthroplasties (TKA) are performed yearly in the United States. Three million are projected to be performed in 2040. Between 15-30% of all patients who undergo TKA have continued pain, reduced quality of life and functional impairments that cannot be attributed to hardware failure/loosening or infection. Treatment options for persistent post TKA pain (failed TKA) are limited. There is a need for minimally invasive, and effective pain and disability modulating interventions for patients with failed TKA. Genicular radiofrequency ablation (GRFA) has been described, refined, and validated as an effective minimally invasive intervention to control refractory knee pain secondary to knee osteoarthritis (OA) as evidenced by three favorable meta-analyses published in 2021 alone.3-5 GRFA is a minimally invasive percutaneous procedure that utilizes thermal energy to coagulate nerves from the knee. Though sometimes used in practice, there is limited research describing and evaluating GRFA for patients with failed TKA. This will be the first trial to evaluate the safety and efficacy of GRFA in patients with failed TKA using a robust study design and up-to-date, evidence-based selection criteria and technique.

NCT ID: NCT05282927 Active, not recruiting - Knee Osteoarthritis Clinical Trials

Implementing Group Physical Therapy (PT) for Veterans With Knee Osteoarthritis (Group PT): Function QUERI 2.0

Group PT
Start date: June 21, 2022
Phase: N/A
Study type: Interventional

Implementing Group Physical Therapy (PT) for Veterans with Knee Osteoarthritis (OA): Function QUERI 2.0 (Group PT) aims to implement, evaluate and sustain Group PT in 16 VA sites using a type III effectiveness-implementation hybrid design framework, which will compare implementation strategies while also gathering information about the clinical intervention and related outcomes.

NCT ID: NCT05280080 Completed - Knee Osteoarthritis Clinical Trials

Exercise With Dual Task in Knee Osteoarthritis

DTOA
Start date: March 21, 2022
Phase: N/A
Study type: Interventional

The purpose of this study is to evaluate the neuromuscular and perceptual responses, pain intensity and performance in patients with severe knee osteoarthritis in a preoperative setting with low-load resistance training with a self-regulated mathematical dual-task.

NCT ID: NCT05280002 Completed - Clinical trials for Osteoarthritis Knees

Adipose-tissue-derived Total-Stromal-cells (TOST) Therapy in Knee Osteoarthritis

Start date: January 1, 2018
Phase: Phase 2
Study type: Interventional

In this phase II Randomized Clinical Trial (RCT), impacts of a single Intra-articular injection of autologous adipose tissue derive total-stromal-cells (TOST) on knee pain, physical function, stiffness, and cartilage thickness assessed and compared changes before and after intervention. Individuals with knee osteoarthritis (KOA) diagnosed by using the American College of Rheumatology (ACR) criteria for Osteoarthritis knee were included in the study. Kellgren-Lawrence (KL) radiological scores were used to define radiological changes and high-frequency musculoskeletal ultrasonogram (MSUS) was used to measure cartilage thickness.

NCT ID: NCT05277883 Not yet recruiting - Knee Osteoarthritis Clinical Trials

Influence of Knee Alignment and Pelvis Rotation on Accuracy of Radiograph Measurements Before Total Knee Arthroplasty

Start date: December 2022
Phase:
Study type: Observational

The aim of this study is to determine the accuracy of long leg standing X-rays with respect to coronal alignment of the knee.

NCT ID: NCT05274932 Completed - Knee Osteoarthritis Clinical Trials

Exercise With Blood Flow Restriction in Knee Osteoarthritis

BFROA
Start date: March 21, 2022
Phase: N/A
Study type: Interventional

The purpose of this study is to evaluate the neuromuscular responses, pain intensity and rate of perceived exertion in patients with severe knee osteoarthritis in a preoperative setting with low-load resistance training with blood flow restriction at different levels of arterial occlusion pressure.

NCT ID: NCT05272748 Recruiting - Knee Osteoarthritis Clinical Trials

The Effects of Conventional Exercise Combined With Core Stabilization Exercise by Telerehabilitation in Patients With Hip and/or Knee Osteoarthritis

Start date: March 16, 2022
Phase: N/A
Study type: Interventional

Age-related hip and knee osteoarthritis is the leading cause of pain and locomotor problems worldwide. There is no definitive solution in the treatment of hip and knee osteoarthritis. In the guidelines of the American Rheumatology Association, pharmacological and non-pharmacological treatment methods are recommended for the treatment of hip and knee osteoarthritis. The effectiveness of different exercise programs for the periarticular muscles in hip and knee osteoarthritis has been proven, but there is no consensus on the superiority of exercise protocols over each other. With the increase in home isolation of individuals due to the COVID-19 pandemic, telerehabilitation applications have gained popularity.In the literature, there is a need for studies investigating the effectiveness of core stabilization exercises in patients with hip and knee osteoarthritis. Therefore, our study will help develop alternative exercises for individuals with hip and knee osteoarthritis. In the literature, there is no study investigating the effectiveness of core stabilization exercises applied with the telerehabilitation method in patients with knee osteoarthritis and comparing them with conventional exercise. According to the data to be obtained as a result of the study, the use of core stabilization exercises in the treatment of hip and knee osteoarthritis will contribute to the literature as an alternative exercise method. The application of these exercises with the telerehabilitation method in the treatment of hip and knee osteoarthritis will highlight new studies in the literature as a unique methodology. Thus, it will contribute to the development of cost-effective rehabilitation methods in the treatment of hip and knee osteoarthritis. The hypotheses of this study are as follows: H0:There is no difference between the effects of combined exercise with telerehabilitation (conventional exercise + core stabilization exercise) and the effects of conventional exercise in the treatment of hip and/or knee osteoarthritis. H1:Combined exercise with telerehabilitation application (conventional exercise + core stabilization exercise) is more effective than conventional exercise in the treatment of hip and/or knee osteoarthritis. Main Purpose: To compare the effects of conventional exercise and core stabilization exercises by telerehabilitation on pain, postural control, functional level, and fear of falling in patients with hip and/or knee osteoarthritis. Secondary Purposes: - To evaluate the effects of core stabilization exercises on pain, postural control, functional level, fear of falling in female patients with hip and/or knee osteoarthritis. - To evaluate the effectiveness of telerehabilitation exercise in female patients with hip and/or knee osteoarthritis. - To determine the possible limitations that may be encountered in the application of exercise by telerehabilitation in female patients with hip and/or knee osteoarthritis and to provide appropriate conditions for the patients.

NCT ID: NCT05272124 Completed - Clinical trials for Osteoarthritis Knees Both

Effects of Hip Abductors Strengthening In Knee Osteoarthritis

Start date: January 1, 2021
Phase: N/A
Study type: Interventional

The aim of my study is to determine the effects of hip abductors strengthening and quadriceps strengthening in comparison with quadriceps strengthening alone in patients with knee osteoarthritis.