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Clinical Trial Summary

Total knee replacement (TKR) is considered the most effective and safe method of radical treatment of late stages of knee osteoarthritis. A well-known problem of TKR is a severe postoperative pain syndrome, which is observed in more than 50% of patients. Femoral nerve block (FNB) is the "gold standard" for continuous postoperative analgesia after total knee replacement, as it is effective in reducing the frequency of use of opioid analgetics and reduce the duration of hospitalization. At the same time, the negative effect of this method is the motor blockade of the quadriceps femoris muscle which leads to functional impairment and is associated with an increased risk of falling. Adductor canal block (ACB) provides adequate analgesia comparable to femoral nerve block. Moreover, ACB doesn't affect the motor function of the quadriceps femoris muscle. The possibility of enhanced recovery after total knee replacement is the reason to compare single-shot adductor canal block and continuous femoral nerve block.


Clinical Trial Description

n/a


Study Design


Related Conditions & MeSH terms


NCT number NCT05487053
Study type Interventional
Source Negovsky Reanimatology Research Institute
Contact Valery Likhvantsev
Phone +79036235982
Email lik0704@gmail.com
Status Recruiting
Phase N/A
Start date February 3, 2024
Completion date July 1, 2026

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