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Clinical Trial Summary

To evaluate the islet function and insulin secretion pattern of post-pancreatitis diabetes mellitus by oral glucose tolerance testing, and to explore the pathophysiological characteristics of PPDM-C which provide evidence for the diagnosis of PPDM-C.


Clinical Trial Description

Blood samples will be collected from patients with chronic pancreatitis by oral glucose tolerance test (steamed bun meal test, SBMT) to assess their pancreatic islet function and insulin secretion pattern, measure other intestinal hormones, exosomes, plasma metabolites, and serum biochemical factors to characterize the pathophysiological features of PPDM-C and provide evidence for the diagnosis of PPDM-C. In order to better understand the glycemic fluctuations in patients with chronic pancreatitis combined with diabetes and guide subsequent treatment, Continuous Glucose Monitoring would be used in patients with chronic pancreatitis who had new-onset diabetes or poor glycemic control. ;


Study Design


Related Conditions & MeSH terms


NCT number NCT05989867
Study type Observational
Source Changhai Hospital
Contact Zhuan Liao
Phone 13061921980
Email liaozhuan@smmu.edu.cn
Status Recruiting
Phase
Start date March 1, 2023
Completion date March 2025

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