Clinical Trials Logo

Clinical Trial Summary

A randomized, crossover, double-blind, two-sessions clinical trial with 30 male volunteers was performed to access pain of local anesthesia after using a topical anesthetic associated or not with prior application of microneedles to the palatal mucosa region


Clinical Trial Description

A randomized, crossover, double-blind, two-sessions clinical trial with 30 male volunteers was performed by applying a microneedle patch and as a negative control the an identical patch but without microneedles sticking out and after the topical anesthetic was applied for in one session 2 minutes and the other session 5 minutes and the investigators evaluated the pain of needle introduction and the injection of the anesthetic. The application force of the microneedles was standardized to 10N by an applicator composed of a 5 mL syringe and a spring. Pain and discomfort associated to the procedure was evaluated with a Visual Analogue Scale (VAS), in these two different moments, introduction of the needle and injection of the anesthetic. ;


Study Design


Related Conditions & MeSH terms


NCT number NCT05267938
Study type Interventional
Source University of Campinas, Brazil
Contact
Status Completed
Phase Phase 1
Start date August 1, 2019
Completion date January 30, 2020

See also
  Status Clinical Trial Phase
Not yet recruiting NCT06381505 - RetracTOR/ Retractor for Image Guided Trans-Oral Surgery
Completed NCT05912335 - Clinical Efficiency of Xanthan Hydrogels Containing Local Anesthetics Encapsulated in Nanostructured Lipid Carries Phase 1
Completed NCT03855397 - Pain and Safety of Microneedles in Oral Cavity N/A
Recruiting NCT05911750 - Prevalence and Clinical Implications of HPV Infection in Male IBD Patients