Measuring Acute Drug Demand in Humans

Status Recruiting

Clinical Trial Summary

This research is being done to evaluate whether suvorexant may reduce the use of, subjective liking, and demand for various drugs.

Clinical Trial Description

This research is being done to evaluate whether suvorexant may reduce the use of, subjective liking, and demand for various drugs. Suvorexant is not approved as a treatment to reduce drug use but is approved by the Food and Drug Administration (FDA) to treat insomnia (trouble falling asleep or staying asleep). This study consists of a screening visit and an approximate 14 to 16 day inpatient (overnight) stay at the Johns Hopkins Bayview Medical Center. Participants will be stabilized on hydromorphone, randomly assigned to receive either suvorexant or placebo, and complete 5 experimental sessions that include taking blinded study medications. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT05829655
Study type	Interventional
Source	Johns Hopkins University
Contact	Justin Strickland, PhD
Phone	(410) 550-1975
Email	jstric14@jhmi.edu
Status	Recruiting
Phase	Early Phase 1
Start date	August 8, 2023
Completion date	October 31, 2027

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