Open Fracture of Tibia Clinical Trial
Official title:
ROLE OF VACUUM ASSISTED CLOSURE IN OPEN TYPE III B TIBIAL FRACTURES
- Evaluate the role of VAC in decreasing the time needed for soft tissue coverage and definitive fixation in open IIIB tibial fractures
- Open fractures are injuries in which the skin and soft-tissue integument are disrupted
and the underlying bone is exposed to the external environment. This communication
results in contamination by microorganisms that can cause deep or superficial infection.
Impaired vascularity, devitalized tissue, and loss of skeletal stability are all factors
leading to increased susceptibility to infection after open fracture [1, 2].
- Current protocols for treating open fractures include early administration of
antibiotics, timely surgical debridement, skeletal stabilization, sterile dressing,
systemic support, and establishment of soft-tissue coverage in a wound environment that
is clean [3, 4-8].
- VAC is being used to obviate the need for, or enhance the success of, free-flap coverage
in open fractures that are significant enough to preclude primary closure, delayed
primary closure, or healing by secondary intention. VAC device and its components, which
in a closed system expose the open wound bed to negative pressure. This pressure removes
edema or hemorrhage, mechanically pulls on the wound edges, decreases in wound surface
area, improves circulation, and enhances proliferation of granulation tissue that filled
the soft tissue defect, enhance debridement of wound debris, reducing the need for
costly free-flap transfers. VAC devices have been used in many surgical disciplines but
only recently have become popular in orthopedics [7, 9,].
;
| Status | Clinical Trial | Phase | |
|---|---|---|---|
| Completed |
NCT03861624 -
Intramedullary Nailing Versus External Fixation in Open Tibia Fractures in Tanzania
|
N/A |