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Effect of Preoperative Oral Carbohydrates on the Insulin Resistance of Elderly Patients

Old Age Clinical Trial

Official title:
Effect of Preoperative Oral Carbohydrates on the Insulin Resistance of Elderly Patients

Clinical Trial Summary

Postoperative cognitive dysfunction (POCD) is more common in older patients, and increased insulin resistance is an important factor for POCD. Fasting before surgery is performed to reduce the incidence of pulmonary aspiration after anesthesia. However, prolonged fasting increases insulin resistance. Recently, it is recommended to minimize fasting times and consume carbohydrate drinks before surgery. Therefore, the investigators investigate whether preoperative carbohydrate drinks can reduce insulin resistance in the elderly patients. Fifty patients (age>65 years) scheduled for arthroplasty will be divided into carbohydrate (n=28) and control (n=28) groups. Randomly selected patients of the carbohydrate group are given 400ml of 12.8 g/100 ml carbohydrate beverage 2-3 hours before their scheduled operation. In contrast, patients in the control group are fasted from water 2 h before surgery according to standard protocol.

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT04206189
Study type Interventional
Source Yonsei University
Contact
Status Completed
Phase N/A
Start date April 1, 2020
Completion date January 18, 2021
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