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Ocular Surface Disease clinical trials

View clinical trials related to Ocular Surface Disease.

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NCT ID: NCT06298890 Recruiting - Cataract Clinical Trials

The Pattern of Dry Eye Disease After Cataract Surgery

Start date: March 2024
Phase:
Study type: Observational

This study is designed to explore dry eye disease (DED) pattern: ocular surface, corneal morphological changes, patients' subjective assessment of DED and their correlations with ocular surface inflammation, pain biomarkers after cataract surgery according to ocular surface lubrication with artificial tears during long-term follow-up.

NCT ID: NCT06256770 Recruiting - Clinical trials for Ocular Surface Disease

Evaluation of the Safety and Efficacy of Rigid Breathable Scleral Contact Lenses for the Correction of Ametropia

Start date: November 1, 2022
Phase:
Study type: Observational

To evaluate the short-term efficacy and safety of scleral contact lens in the clinical treatment of patients with irregular astigmatism after corneal transplantation by analyzing ocular parameters and ocular surface conditions of patients after corneal transplantation.

NCT ID: NCT05195801 Recruiting - Clinical trials for Ocular Surface Disease

Optic Nerve Diameter and Intraocular Pressure Changes in Patients Undergoing Vitrectomy Under General Anesthesia

Start date: January 1, 2022
Phase:
Study type: Observational

This study aimed to measure optic nerve sheath changes in the intraoperative period in patients who underwent vitrectomy surgery and to investigate the intraoperative factors that may affect this. Standard anesthesia protocol will be applied to all patients participating in the study. Optic nerve sheath diameter measurements of the patients taken to the operating room will be made on the operating table by ultrasonography method. Standard anesthesia induction will be performed following SpO2 and ECG monitoring in routine anesthesia monitoring. Depth of anesthesia will be evaluated with routine hemodynamic data.

NCT ID: NCT05145959 Recruiting - Dry Eye Clinical Trials

Meibomian Gland Probing in the Sub-Acute Phase of Patients With Stevens-Johnson Syndrome/Toxic Epidermal Necrolysis

Start date: December 1, 2021
Phase: N/A
Study type: Interventional

The investigators' aim is to study the effects of mechanical expression of meibomian glands on eyelid disease, ocular surface health in the subacute phase of SJS/TEN. The primary outcome is to use meibomian gland imaging to assess the health and caliber of the meibomian glands of both lower eyelids, between the treated and non-treated eyes before and after the intervention. Monitoring of outcomes will be measured by comparing the results of meibography at the initial visit and at the 6-month follow-up. The secondary outcome assessed will be patient symptoms. The Ocular Surface Disease Index survey will be administered before each treatment and patients will be asked to differentiate their symptoms between the two eyes, both before and after the intervention. The investigators hypothesize that mechanical expression of meibomian glands within the first 6 months of SJS/TEN onset will significantly improve ocular surface disease and symptoms in those patients.

NCT ID: NCT04354545 Recruiting - Glaucoma Clinical Trials

Treatment of Ocular Discomfort in Glaucoma Patients Using Multiple Topical Medications

Start date: April 1, 2021
Phase:
Study type: Observational

To evaluate glaucoma patients' response to treatment with Xiidra, an FDA-approved drug for ocular surface discomfort, which will be prescribed as standard of care treatment.

NCT ID: NCT04010422 Recruiting - Autism Clinical Trials

Ocular Function in Autism Spectrum Disorder

Start date: May 15, 2019
Phase:
Study type: Observational

This study will investigate the visual function in individuals with ASD, with a particular focus on the ocular surface condition and visual function assessment.

NCT ID: NCT02894489 Recruiting - Keratoconus Clinical Trials

Changes of Visual Function, Ocular Surface Structures and Physiology After Long-Termed Contact Lens Wear

Start date: August 2016
Phase: N/A
Study type: Interventional

Our study is aimed to observe the long termed effect of contact lens wear on ocular surface, especially focused on visual function and ocular inflammation mediators.

NCT ID: NCT01284439 Recruiting - Glaucoma Clinical Trials

Hydroxypropylmethylcellulose 0.3% and Sodium Hyaluronate 0.18% for Ocular Surface Disease in Glaucoma

Start date: January 2011
Phase: N/A
Study type: Interventional

To study effect of hydroxypropylmethylcellulose 0.3% and sodium hyaluronate 0.18% in the treatment of ocular surface disease in glaucoma patients.