Clinical Trials Logo

Ocular Surface Disease clinical trials

View clinical trials related to Ocular Surface Disease.

Filter by:

NCT ID: NCT06375343 Not yet recruiting - Dry Eye Disease Clinical Trials

Study to Evaluating PRO-240 Ophthalmic Solution Compared to Optive®

Start date: October 30, 2024
Phase: Phase 1
Study type: Interventional

This is a phase I clinical study to evaluating safety and tolerability of PRO-240 ophthalmic solution through the incidence of unexpected adverse events, as well as through changes in Best Corrected Visual Acuity (BCVA), and the incidence of stinging after its administration, compared to Optive®.

NCT ID: NCT06370585 Not yet recruiting - Dry Eye Disease Clinical Trials

Clinical Study to Evaluate the Safety and Tolerability of PRO-229 Ophthalmic Solution Compared to Lagricel® Ofteno PF

Start date: May 30, 2024
Phase: Phase 1
Study type: Interventional

This is a phase I study evaluating safety and tolerability of PRO-229 ophthalmic solution through he incidence of unexpected adverse events, changes in Best Corrected Visual Acuity (BCVA), incidence of chemosis, and changes in ocular surface staining using the Sjögren's International Collaborative Clinical Alliance (SICCA) Ocular Staining Score (OSS) scale compared to Lagricel® Ofteno PF in clinically healthy subjects.

NCT ID: NCT06355128 Active, not recruiting - COVID-19 Clinical Trials

A Cross-sectional Study of Ocular Manifestations During the Covid-19 Pandemic in Hubei Province

Start date: January 1, 2024
Phase:
Study type: Observational [Patient Registry]

To investigate the clinical features of ocular manifestations during the novel coronavirus pneumonia pandemic in Hubei at the end of 2022

NCT ID: NCT06298890 Recruiting - Cataract Clinical Trials

The Pattern of Dry Eye Disease After Cataract Surgery

Start date: March 2024
Phase:
Study type: Observational

This study is designed to explore dry eye disease (DED) pattern: ocular surface, corneal morphological changes, patients' subjective assessment of DED and their correlations with ocular surface inflammation, pain biomarkers after cataract surgery according to ocular surface lubrication with artificial tears during long-term follow-up.

NCT ID: NCT06256770 Recruiting - Clinical trials for Ocular Surface Disease

Evaluation of the Safety and Efficacy of Rigid Breathable Scleral Contact Lenses for the Correction of Ametropia

Start date: November 1, 2022
Phase:
Study type: Observational

To evaluate the short-term efficacy and safety of scleral contact lens in the clinical treatment of patients with irregular astigmatism after corneal transplantation by analyzing ocular parameters and ocular surface conditions of patients after corneal transplantation.

NCT ID: NCT06013436 Completed - Dry Eye Clinical Trials

AST Combined With 0.05% Cyclosporin Eye Drop Improve Corneal Nerve Density in Patients With SS Dry Eye

AST/SS
Start date: June 1, 2022
Phase:
Study type: Observational

The objective of the present study was to evaluate the efficacy of autologous serum tears combined with 0.05% cyclosporin eye drop in treating Sjögren's syndrome dry eye and their effect on corneal nerves. We assessed the impact of 12-week AST combined with 0.05% cyclosporin eye drop treatment on signs, symptoms, and sub-basal nerve density (SND) in patients with dry eyes related to Sjogren's syndrome.

NCT ID: NCT05938985 Active, not recruiting - Dry Eye Clinical Trials

Croatian Version of the Ocular Surface Disease Index Questionnaire (OSDI)

Cro-OSDI
Start date: June 12, 2023
Phase:
Study type: Observational

Ocular Surface Disease Index (OSDI) Questionnaire is an important tool for the diagnosis of dry eye disease. Croatian version is yet not available. With a permission of AbbVie company investigators want to make a Croatian version of the Ocular Surface Disease Index Questionnaire (Cro-OSDI).

NCT ID: NCT05832996 Completed - Clinical trials for Ocular Surface Disease

Cool vs Room-temperature Artificial Tears

Start date: March 1, 2022
Phase: Phase 4
Study type: Interventional

Background and Objective: To evaluate the efficacy of cooled versus room temperature artificial tears in reducing post intravitreal injection (IVI) ocular discomfort. Patients and Methods: Patients receiving IVI were randomized to either cooled or room temperature tears intervention groups. Both groups rated their ocular discomfort following IVI before intervention and again after administration of cooled or room temperature tears.

NCT ID: NCT05528016 Completed - Dry Eye Clinical Trials

Short and Long-term Results of Skin Versus Skin Plus Orbicularis Resection Blepharoplasty

Start date: May 1, 2021
Phase: N/A
Study type: Interventional

This study aims to evaluate the short and long-term effects of skin-only and skin+muscle excision blepharoplasty on corneal nerves, dry eye parameters, meibomian glands, and eyebrow position.

NCT ID: NCT05319470 Completed - Glaucoma Clinical Trials

Ocular Surface Disease and IOP Monitoring With Travoprost Without Conservatives

Start date: March 15, 2022
Phase:
Study type: Observational [Patient Registry]

Primary objective of this study is to study the efficacy of travoprost without preservatives in the treatment of glaucoma patients and to monitor the ocular surface.