PSLT Compared to Prostaglandin Analogue Eye Drops

Status Recruiting

Clinical Trial Summary

This study aims to compare the efficacy of PSLT and the topical use of prostaglandin-like hypotensive eye drops in the treatment of ocular hypertensive or glaucomatous patients in decreasing intraocular pressure and measuring changes in functional, structural and biomechanical parameters evaluated by computerized perimetry and optical coherence tomography (OCT) related to pressure change resulting from treatments

Clinical Trial Description

Patients with a diagnosis of ocular hypertension or bilateral glaucoma, naive or on treatment with up to two classes of hypotensive eye drops will be invited to participate in the study. These patients will have both eyes included in the study. A randomization will be made to allocate one eye to receive treatment with PSLT (treatment group), while the contralateral eye will receive treatment with prostaglandin eye drops (control). Patients will be followed up for 12 months and periodically tonometry, computerized perimetry, water overload test and OCT will be performed. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT05241938
Study type	Interventional
Source	Federal University of Rio Grande do Sul
Contact	Helena Pakter, MD, PhD
Phone	+55-51-991226968
Email	Hmpakter@hcpa.edu.br
Status	Recruiting
Phase	N/A
Start date	September 1, 2021
Completion date	December 20, 2022

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