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Ocular Hypertension clinical trials

View clinical trials related to Ocular Hypertension.

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NCT ID: NCT01302249 Completed - Glaucoma Clinical Trials

AR-12286 in Combination With Latanoprost

Start date: February 2011
Phase: Phase 2
Study type: Interventional

This is a double-masked, randomized, multi-center, active-controlled, crossover comparison of the addition of AR-12286 or timolol to latanoprost in the treatment of elevated intraocular pressure (IOP).

NCT ID: NCT01298700 Completed - Glaucoma Clinical Trials

Long-Term Safety of Bimatoprost Ophthalmic Solution in Patients With Glaucoma or Ocular Hypertension

Start date: May 31, 2011
Phase: Phase 4
Study type: Interventional

This study will evaluate the long-term safety of bimatoprost 0.01% ophthalmic solution compared with bimatoprost 0.03% ophthalmic solution in patients with glaucoma or ocular hypertension.

NCT ID: NCT01298687 Completed - Ocular Hypertension Clinical Trials

Divided Dose of TRAVATAN®

Start date: February 2011
Phase: Phase 2
Study type: Interventional

The purpose of this study is to compare the incremental dosing of travoprost ophthalmic solution versus once a day dosing of TRAVATAN® in lowering intraocular pressure (IOP) in patients with open-angle glaucoma (OAG) or ocular hypertension (OHT).

NCT ID: NCT01297920 Completed - Ocular Hypertension Clinical Trials

Three Month Efficacy/Safety Study With a 3-Month Safety Extension of Brinzolamide 1%/Brimonidine 0.2% vs. Brinzolamide 1% or Brimonidine 0.2%

Start date: March 2011
Phase: Phase 3
Study type: Interventional

The purpose of this study was to evaluate the safety and efficacy of a new ophthalmic suspension (Brinz/Brim) in lowering intraocular pressure (IOP) relative to its individual active components in subjects with open-angle glaucoma and/or ocular hypertension.

NCT ID: NCT01297517 Completed - Ocular Hypertension Clinical Trials

Efficacy and Safety Study of Brinzolamide 1%/Brimonidine 0.2% vs. Brinzolamide 1% and Brimonidine 0.2%

Start date: February 2011
Phase: Phase 3
Study type: Interventional

The purpose of this study was to evaluate the efficacy and safety of a fixed combination of Brinzolamide/Brimonidine in lowering intraocular pressure (IOP) relative to each of its individual active components in patients with open-angle glaucoma and/or ocular hypertension.

NCT ID: NCT01292460 Completed - Ocular Hypertension Clinical Trials

Tafluprost-Timolol Preservative-free Fixed Dose Combination (FDC) Superiority Study Against Monotherapies

Start date: February 2011
Phase: Phase 3
Study type: Interventional

The purpose of this study is to compare the efficacy and safety of the preservative-free fixed tafluprost-timolol combination to those of tafluprost and timolol alone. This study will enroll patients who have ocular hypertension or glaucoma and who are using timolol or prostaglandin. The study medication period is 6 months, but the primary evaluation of efficacy is done at 3 months.

NCT ID: NCT01291108 Completed - Ocular Hypertension Clinical Trials

Safety and Efficacy of AGN-210669 Ophthalmic Solution Compared With Bimatoprost Ophthalmic Solution in Patients With Open-Angle Glaucoma or Ocular Hypertension

Start date: April 2011
Phase: Phase 2
Study type: Interventional

This study will evaluate the safety and efficacy of AGN-210669 ophthalmic solution compared with bimatoprost ophthalmic solution (Lumigan®) as monotherapy and adjunctive therapy in patients with primary open-angle glaucoma or ocular hypertension.

NCT ID: NCT01284166 Withdrawn - Glaucoma Clinical Trials

Safety and Efficacy of Triple Combination Therapy With Dorzolamide Hydrochloride / Brimonidine Tartrate / Timolol Ophthalmic Solution in Patients With Glaucoma or Ocular Hypertension

Start date: July 2013
Phase: Phase 3
Study type: Interventional

This study will investigate the safety and efficacy of Triple Combination Therapy with dorzolamide hydrochloride/brimonidine tartrate/timolol ophthalmic solution in patients with glaucoma or ocular hypertension who have elevated IOP on dorzolamide hydrochloride/timolol maleate combination therapy.

NCT ID: NCT01281020 Completed - Ocular Hypertension Clinical Trials

Adherence With Fixed Versus Unfixed Glaucoma Therapy

Start date: May 2009
Phase:
Study type: Observational

A 6-month, parallel, non-interventional trial investigating the level of adherence and the impact of dosing in open-angle glaucoma patients who receive either unfixed therapy with latanoprost once in the evening and timolol twice daily, or latanoprost/timolol fixed combination therapy once in the evening. All patients participating in this observational study will be monitored for their adherence with the use of Medication Event Monitoring System (MEMS). At the end of treatment periods treatment satisfaction will be assessed with selected questions from the Treatment Satisfaction Survey-Intraocular Pressure survey. This study will monitor objectively, for the first time, adherence and intraocular pressure control with fixed versus unfixed therapy. Finally it will help us to elucidate the impact of dosing (once-a-day versus three-times-daily) on the level of adherence in glaucoma.

NCT ID: NCT01279083 Completed - Ocular Hypertension Clinical Trials

Safety and Efficacy Trial to Treat Open-Angle Glaucoma or Ocular Hypertension

Start date: January 2011
Phase: Phase 1/Phase 2
Study type: Interventional

To investigate the safety and efficacy of DE-112 in lowering intraocular pressure in subjects with primary open-angle glaucoma or ocular hypertension.