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Clinical Trial Summary

The obstructive sleep apnea syndrome (OSAS) involves recurrent sleep-related upper airways (UA) collapse. UA mechanical properties and neural control are altered, imposing a mechanical load on inspiration. UA collapse does not occur during wakefulness, hence arousal-dependent compensation. Experimental inspiratory loading in normal subjects elicits respiratory-related cortical activity during wakefulness. The objective of this study is to test whether awake OSAS patients would exhibit a similar cortical activity. Whether or not such cortical compensatory mechanisms have cognitive consequences would be also analyze.


Clinical Trial Description

n/a


Study Design


Related Conditions & MeSH terms


NCT number NCT05147649
Study type Interventional
Source CHU de Reims
Contact Claire Launois
Phone 3 26 78 83 70
Email claunois@chu-reims.fr
Status Recruiting
Phase N/A
Start date March 2, 2023
Completion date July 2, 2026

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