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Obstetric Pain clinical trials

View clinical trials related to Obstetric Pain.

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NCT ID: NCT05498025 Completed - Pain, Acute Clinical Trials

The Effect of a Charcoal Deactivation Pouch on Opioid Disposal After Cesarean Delivery

Start date: February 21, 2023
Phase: N/A
Study type: Interventional

Background: There is scarce literature investigating how patients dispose of unused opioid supplies after their cesarean postoperative pain has faded. The Office of the Surgeon General has identified research on the prevention of opioid use disorder area as well as research on the management of pain as a "Surgeon General Priority" that needs urgent investigation. Hypothesis: At least 33% of postpartum women discharged home with an opioid prescription and a drug deactivation pouch will use the pouch to dispose of remaining opioids within 30 days of delivery. Methods: This is a prospective single arm interventional pilot study.

NCT ID: NCT05447455 Completed - Obstetric Pain Clinical Trials

TAP Block vs LAWI for Analgesia Post-cesarean Section

Start date: January 1, 2021
Phase: N/A
Study type: Interventional

Adequate pain control after cesarean delivery is a significant concern both for parturients and obstetric anesthesiologists. Transversus Abdominis Plane (TAP) block and local Wound infiltration with anesthetics are alternatives for reducing the severity of pain, total analgesic consumption, and opioid side effects. Both the TAP block and wound infiltration are superior to placebo; however, it is unknown which provides better analgesia after cesarean delivery because of a scarcity of randomized clinical trials. So, we hypothesized that the TAP block would decrease postoperative pain and postoperative cumulative opioid consumption at 24 hours

NCT ID: NCT04637386 Completed - Obstetric Pain Clinical Trials

TAP Block vs LAWI for Analgesia Post-cesarean Section: RCT

Start date: January 1, 2021
Phase: N/A
Study type: Interventional

Adequate pain control after cesarean delivery is a significant concern both for parturients and obstetric anesthesiologists. Transversus Abdominis Plane (TAP) block and local Wound infiltration with anesthetics are alternatives for reducing the severity of pain, total analgesic consumption, and opioid side effects. Both the TAP block and wound infiltration are superior to placebo; however, it is unknown which provides better analgesia after cesarean delivery because of a scarcity of randomized clinical trials. So, we hypothesized that the TAP block would decrease postoperative pain and postoperative cumulative opioid consumption at 24 hours

NCT ID: NCT04443569 Completed - Postoperative Pain Clinical Trials

Lidocaine Patches After Cesarean Section

LPACS
Start date: October 10, 2021
Phase: Phase 3
Study type: Interventional

The aim of this study is to investigate the impact of using lidocaine patches after cesarean section on pain control and opioid use in the immediate post-operative period. The hypothesis is the use of lidocaine patches in the immediate post-operative period will lead to a decrease in the use of opioids as pain control compared to patients that do not have a lidocaine patch in place. Additionally, the a decrease in the visual analog pain score compared to women who do not use a lidocaine patch in the immediate post-operative period following cesarean delivery is anticipated.

NCT ID: NCT04037085 Completed - Opioid Use Clinical Trials

Ketamine to Improve Recovery After Cesarean Delivery - Part 1

KINETIC
Start date: October 9, 2019
Phase: Phase 2
Study type: Interventional

The objective of this study is evaluate the breastmilk transfer and pharmacokinetics (Part 1) and effectiveness (Part 2) of a post-cesarean delivery intravenous ketamine bolus-and-infusion strategy, as a preventive analgesic modality to reduce pain and opioid requirements. In Part 1, physiochemical analysis of pharmacokinetic/pharmacodynamic (PK/PD) and breastmilk transfer of ketamine and its metabolites will be assessed. Additionally calculated estimations for neonatal and infant exposure will be assessed. In Part 2, PK/PD assessments will continue in a larger cohort; endpoints will also include postpartum pain, depression scores, central sensitization measures, patient-reported postpartum recovery scores, breastfeeding, and parent-infant bonding, assessed in the acute post-cesarean period and up to 12 weeks postpartum in a randomized controlled trial.

NCT ID: NCT03652116 Completed - Obstetric Pain Clinical Trials

Bupivacaine Verus Pethidine for Post Cesarean Section Pain Relief

Start date: April 21, 2017
Phase: Phase 2/Phase 3
Study type: Interventional

The aim of this study is to compare between the effect of wound infiltration with bupivacaine or pethidine for post cesarean section pain relief.

NCT ID: NCT03634111 Completed - Obstetric Pain Clinical Trials

The Effect of the Transversus Abdominis Plane Block to Postoperative Analgesia for Cesarean Section

TAP
Start date: July 10, 2017
Phase: N/A
Study type: Interventional

The transversus abdominis plane block (TAP block) has effect to postoperative analgesia for cesarean section with spinal anesthesia but it was limited for cesarean section with general anesthesia. The hypothesis that this technique has effect to postoperative analgesia for cesarean section with general anesthesia and it could reduce 50% of total morphine consumption during 24 hours after surgery.

NCT ID: NCT03596333 Completed - Labor Pain Clinical Trials

Color Doppler Ultrasound to Locate Needle in Labor Epidural

Start date: May 28, 2018
Phase:
Study type: Observational

Color Flow Doppler (CFD) utilizes Doppler information obtained from signals sent to and received from a transducer. This information is color-encoded and then displayed as color on an overlay of the two-dimensional image. The color scale represents both speed and direction of flow within a discrete area of the image. CFD has been recently used to determine the position of the epidural catheter. However its role in labor epidural has yet to be defined. This study describes the use of CFD to confirm the position of the tip of the epidural needle in the context of labor analgesia. This study hypothesized that CFD is a feasible method for identifying proper epidural needle placement prior to epidural catheter advancement.

NCT ID: NCT03502642 Completed - Obstetric Pain Clinical Trials

Ropivacaine Continuous Wound Infusion Versus Intrathecal Morphine for Postoperative Analgesia After Cesarean Delivery

Start date: May 29, 2017
Phase: Phase 4
Study type: Interventional

Cesarean delivery is one of the most common surgical procedures, performed at an increasingly high rate. It is associated with intense postoperative pain that may hamper the rehabilitation process and interfere with patient satisfaction and care provided to the newborn. Therefore, control of perioperative pain with multimodal regimens using local anesthetic may be important in short- and long-term convalescence after surgery. Opioid-based regimens are the "gold standard" of cesarean delivery analgesia. However, spinal and epidural opioids have a ceiling effect. Wound infiltration with local anesthetics has been used widely in the multimodal approach of pain relief. Continuous wound infusion with local anesthetic through a multiorifice catheter increases the duration of action and efficacy of local surgical wound infiltration compared with a one-time wound injection of local anesthetic. After cesarean delivery, Local anesthetic continuous wound infusion would be associated with better reduction in pain scores when compared to intrathecal morphine . Therefore, an assessor and patient blinded, randomized study that aimed to compare the efficacy and side effects of these analgesia techniques was conducted.

NCT ID: NCT03495531 Completed - Pain Clinical Trials

Virtual Reality in Obstetric Patients

Start date: July 3, 2018
Phase: N/A
Study type: Interventional

The purpose of this study is to determine if non-invasive distracting devices (Virtual Reality headset) are more effective than the standard of care (i.e., no technology based distraction) for preventing anxiety and pain scores in women who are undergoing child laboring procedures. The anticipated primary outcome will be a reduction of pregnant females overall anxiety and pain scores before and after such procedure(s), including but not limited to epidural/combined spinal epidural (CSE), IV placement and/or labor.