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Obstetric Labor, Premature clinical trials

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NCT ID: NCT04362579 Completed - Pregnancy Preterm Clinical Trials

Advanced Multi-Modal Wearable Sensing for the Prediction of Pre-Term Labor

Start date: January 1, 2021
Phase:
Study type: Observational

Percent agreement of vital signs monitoring between the experimental sensor and standard of care monitoring

NCT ID: NCT04296591 Completed - Preterm Birth Clinical Trials

This Study Was to Investigate the Efficacy of Fetal Right Heart Doppler Findings in Determination of Pulmonary Maturity

Start date: January 1, 2017
Phase:
Study type: Observational [Patient Registry]

Objective: The aim of this study was to investigate the efficacy of fetal right heart doppler findings in determination of pulmonary maturity. Materials and Methods: Pregnant women refered to the Department of Obstetrics and Gynecology at Karadeniz Technical University were included in the study. Pregnant women with pregestational or gestational diabetes mellitus, morbid obesity, thyroid dysfunction and fetal abnormality aneuploidy were not included in the study. The study was planned on women with late preterm and term pregnancy. Late preterm cases between 34-37 weeks were included in study group and term cases over 37 weeks were in control group. The doppler findings of main pulmonary artery and right pulmonary artery, mitral valve e/a wave ratio and lamellar body count were determined as the main outcomes. During caesarean section, 5cc amniotic fluid was taken to measure lamellar bodies count. Perinatal results of patients were recorded. p<0.05 was considered as statistical significance.

NCT ID: NCT04177992 Completed - Hypoxia Clinical Trials

Servo Controlled Oxygen Targeting Study

SCO2T
Start date: January 16, 2020
Phase: N/A
Study type: Interventional

Most premature babies require oxygen therapy. There is uncertainty about what oxygen levels are the best. The oxygen levels in the blood are measured using a monitor called a saturation monitor and the oxygen the baby breathes is adjusted to keep the level in a target range. Although there is evidence that lower oxygen levels maybe harmful, it is not known how high they need to be for maximum benefit. Very high levels are also harmful. Saturation monitors are not very good for checking for high oxygen levels. For this a different kind of monitor, called a transcutaneous monitor, is better. Keeping oxygen levels stable is usually done by nurses adjusting the oxygen levels by hand (manual control). There is also equipment available that can do this automatically (servo control). It is not known which is best. Studies of automated control have shown that infants spend more time within their intended target oxygen saturation range. These have not included measurements of transcutaneous oxygen. The investigators aim to show the transcutaneous oxygen levels as well as the oxygen saturation levels when babies have their oxygen adjusted manually or automatically.

NCT ID: NCT04095507 Completed - Preterm Labor Clinical Trials

Uterocervical Angle in Patients With Preterm Premature Rupture of the Membranes

Start date: January 1, 2019
Phase: N/A
Study type: Interventional

To evaluate the performance of uterocervical angle (UCA) in the prediction of labor timing in patients with preterm premature rupture of the membranes

NCT ID: NCT03935152 Completed - Preterm Labor Clinical Trials

Oral Dydrogesterone in the Management of Preterm Labor

Start date: May 11, 2019
Phase: Phase 4
Study type: Interventional

This study evaluates the addition of oral dydrogesterone to standard treatment in the treatment of preterm labor. Half of participants will receive oral dydrogesterone and standard treatment, while the other half will receive oral placebo and standard treatment.

NCT ID: NCT03923023 Completed - Preterm Birth Clinical Trials

Impact of the PREEMI Package on Neonatal Mortality

PREEMI
Start date: November 1, 2014
Phase:
Study type: Observational [Patient Registry]

The purpose of this Quality Improvement initiative is to reduce severe morbidity and mortality among premature infants through proven and cost-effective clinical management during the antenatal, intrapartum, and postpartum periods. In order to reduce neonatal mortality and morbidity due to preterm birth complications, health facilities must be able to identify and manage women in preterm labor, accurately administer medications, and provide high-quality postnatal care.

NCT ID: NCT03828695 Completed - Preterm Labor Clinical Trials

Uterocervical Angle in Idiopathic Polyhydramnios

Start date: January 1, 2019
Phase: N/A
Study type: Interventional

To evaluate the performance of uterocervical angle (UCA) in the prediction of preterm labor in isolated polyhydramnios

NCT ID: NCT03785795 Completed - Preterm Labor Clinical Trials

Multichannel EMG Diagnosing True Preterm Labor

PTL
Start date: November 25, 2018
Phase:
Study type: Observational

We have designed new electromyography sensors for measuring uterine activity. These sensors are directional - they preferentially report uterine muscle contractions at specific locations, called regions. By measuring the synchronization of the regions of the uterus during contractions we intend to non-invasively determine if any patient is in-labor or not-in-labor. Accurately diagnosing true preterm labor allows timely intervention to avoid preterm birth; Accurately diagnosing false preterm labor avoids needlessly treating patients who would not benefit.

NCT ID: NCT03542552 Completed - Placenta Previa Clinical Trials

Nifedipine Versus Magnesium Sulfate for Prevention of Preterm Labor in Symptomatic Placenta Previa

Start date: June 1, 2018
Phase: Phase 3
Study type: Interventional

Antepartum hemorrhage is defined as bleeding from or within the female genital tract, occurring from 28+0 weeks of pregnancy and till delivery of the fetus. it occurs in 3-5% of pregnancies and is an important cause of perinatal and maternal morbidity and mortality worldwide

NCT ID: NCT03539562 Completed - Labor Pain Clinical Trials

Therapeutic Rest to Delay Admission in Early Labor: A Prospective Study on Morphine Sleep

Start date: September 27, 2017
Phase:
Study type: Observational

This will be a prospective study on labor characteristics, and obstetric and neonatal outcomes in women who accept and women who decline morphine as a form of pain management in labor. The study will also investigate patient satisfaction with this form of analgesia. The participants will be those who accept morphine and promethazine and those who decline morphine and promethazine for pain control.