Clinical Trials Logo

Obstetric Labor, Premature clinical trials

View clinical trials related to Obstetric Labor, Premature.

Filter by:
  • Active, not recruiting  
  • Page 1

NCT ID: NCT06168149 Active, not recruiting - Clinical trials for Respiratory Distress Syndrome

The Relationship of Fetal Lung Elastography Values With the Development of Respiratory Distress in Cases of Preterm Labor

Start date: September 6, 2023
Phase:
Study type: Observational

The aim of this study was to compare fetal lung elastography (FAE) values between groups with and without Respiratory Distress Syndrome (RDS) in preterm neonates and to evaluate the potential of FAE to predict the risk of developing RDS.

NCT ID: NCT06074601 Active, not recruiting - Preterm Birth Clinical Trials

MIRACLE of LIFE Study

MoL
Start date: August 1, 2021
Phase:
Study type: Observational

The goal of this observational study is to develop and validate cell-free RNA-based biomarkers for predicting a variety of adverse pregnancy outcomes in a pregnant person population. The main question it aims to answer are: 1. Can cell-free RNA-based biomarkers predict which pregnant people are at greatest risk of developing adverse pregnancy outcomes (e.g., preterm birth, preeclampsia)? 2. What is the performance of such biomarkers when predicting an adverse pregnancy outcome (e.g., sensitivity, specificity, PPV, NPV, TPR)?

NCT ID: NCT04313673 Active, not recruiting - Preterm Labor Clinical Trials

Transabdominal Cervical Length Predict Preterm Labor During Routine Antenatal Screening

Start date: March 10, 2020
Phase:
Study type: Observational

Sonographically, cervical length measurement is widely used in obstetrics. Studies have revealed that early detection of short cervix can be a predictor of predicting preterm labor. Transvaginal ultrasonography has been shown as a reference method for the recognition of the short cervix, as well as it may be useful in the transabdominal evaluation in the studies conducted. In addition to the advantages of transvaginal evaluation, it is time consuming and disadvantages of some women during anxiety and discomfort during this procedure. Transabdominal ultrasonography, which provides a non-invasive evaluation, is more preferred by some patients than transvaginal. The aim of this study is to investigate the value of the cervical length measured by transabdominal route, which is a more acceptable method for pregnant women, in predicting preterm birth.

NCT ID: NCT04301518 Active, not recruiting - Preterm Birth Clinical Trials

Prematurity Risk Assessment Combined With Clinical Interventions for Improving Neonatal outcoMEs

PRIME
Start date: November 6, 2020
Phase: N/A
Study type: Interventional

This prospective, randomized, controlled study evaluates the safety and efficacy of a preterm birth (PTB) prevention strategy versus standard of care pregnancy management to reduce the incidence of adverse pregnancy outcomes.

NCT ID: NCT03369262 Active, not recruiting - Preterm Labor Clinical Trials

PoC Study of OBE022 in Threatened Preterm Labour

PROLONG
Start date: January 10, 2018
Phase: Phase 2
Study type: Interventional

This is a proof-of-concept study in 2 parts. In Part A, patients will receive OBE022 open-label in order to assess the safety and pharmacokinetics in pregnant women with spontaneous preterm labour with a gestational age between 28 0/7 and 33 6/7 weeks. Part B has a double-blind, randomised, placebo controlled, parallel group and multicentre design and will assess the efficacy, safety and pharmacokinetics in pregnant women with threatened spontaneous preterm labour with a gestational age between 24 0/7 and 33 6/7 weeks. All patients in part A and part B must receive atosiban infusion for 48 hours as standard of care treatment. Patients from Part A will receive OBE022 open label. Patients from Part B will be randomised to receive OBE022 or matching placebo. IMP treatment duration will be up to 7 days. IMP treatment will be stopped in case of delivery prior to Day 7.

NCT ID: NCT02108886 Active, not recruiting - Preterm Labor Clinical Trials

Pilot Study Testing a New Strategy for Management of Spontaneous Preterm Birth

EAU2-Mtlk
Start date: December 2011
Phase: Phase 2
Study type: Interventional

Preterm birth is a major public health problem, and actual treatments are not very efficient. The purpose of this study is to test the efficiency of a combined use of Montelukast and Nifedipine to treat preterm labor. Investigators aim to reduce uterine contractions more efficiently than with the use of Nifedipine only.