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Observational Study clinical trials

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NCT ID: NCT06361602 Not yet recruiting - Observational Study Clinical Trials

Exploring the Effectiveness and Factors Affecting the Collection of Single Nucleated Cells From Different Volunteers

SYX-AN-01
Start date: May 1, 2024
Phase:
Study type: Observational

1. 80 cases of healthy donors were subjected to peripheral blood single nucleated cells (PBMC) collection and analyzed the effects of age, body mass index (BMI), blood routine indexes before collection, collection of circulating blood volume, volume of processed blood and the number of circulations, etc., on the PBMC obtained from both men and women, and explored the effects of PBMC collection in different volunteers and the factors affecting the collection. and the influencing factors. 2. The data obtained will provide a reference for the MNC threshold for the subsequent clinical trials of immunocell therapy in hospitals. 3. From the screening of volunteers, PBMC collection and transportation conditions and other specific details of the operation, risk assessment and the establishment of a safe operation standard process, for the hospital to carry out subsequent clinical trials of immune cell therapy to provide an effective reference.

NCT ID: NCT06316752 Recruiting - Observational Study Clinical Trials

The Natural History of Sialidosis Type I

Start date: March 15, 2022
Phase:
Study type: Observational

Sialidosis type 1 is an autosomal recessive disorder caused by bialleic NEU1 gene mutations. Patients with sialidosis type I present variable neurological and eye dysfunction and the progression rate is variable. The goal of this protocol is to assess the neurological and ophthalmological status of these patients and characterize the clinical and laboratory abnormalities in order to determine the natural history of the disease. Patients will be followed every 6 month with comprehensive clinical, neurological and ophthalmological examinations combined with neuropsychological, blood, radiological and electrophysiological tests.

NCT ID: NCT05654974 Completed - Observational Study Clinical Trials

Sexual Habits Affect Penis Size in Adulthood

ShiP
Start date: December 1, 2019
Phase:
Study type: Observational

Purpose: to assess in Kazakh adult males erect penis sizes, and study an influence of their natural physiological events and behavioral habits during their growing ages on their penile sizes nowadays. Study Design: An observational cross-sectional survey pilot study using a correlational design with the intention-to-treat principle.

NCT ID: NCT05359367 Recruiting - Stroke Clinical Trials

A Novel Approach to Enhance True Recovery After Stroke

Start date: November 29, 2023
Phase:
Study type: Observational

The purpose of this study is to elucidate pathophysiological mechanisms behind gait disturbances during the early recovery phase after hemiparetic stroke to identify targets for new treatment strategies. Using an explorative, observational study design, pathophysiological mechanisms at play during the early recovery phase will be monitored, by repeated clinical assessments during inpatient rehabilitation as well as examinations of muscle activation patterns, kinematics of walking, corticospinal and reticulospinal function < 1 month, 3 and 6 months after hemiparetic stroke. Inclusion: Eligible patients will have suffered a stroke, verified by CT or MRI examination and are admitted to inpatient care at the University Department of Rehabilitation Medicine Danderyd Hospital (RUDS). Thirty patients will be included consecutively. With an anticipated loss of 4-10 patients, at least 20 are expected to complete the study. The clinical assessment protocols include standardized measures for the assessment of clinical and self-perceived aspects of functioning and disability. These assessments will be performed and repeated < 1 month, at 3 months and 6 months post-stroke by a therapist not responsible for rehabilitation interventions. At each of these assessment instances, laboratory movement analysis including electromyography (EMG) and ultrasound of the lower extremity muscle will be performed. In addition, a short assessment of body function and activity will be performed weekly during inpatient rehabilitation.

NCT ID: NCT05135013 Not yet recruiting - Observational Study Clinical Trials

The Association of Hormonal Intake and Demographic Factors With Breast Cancer Risk. An Egyptian Case-controlled Study

Start date: November 16, 2021
Phase:
Study type: Observational

The aim of the current study is to investigate the association between hormonal intake, occupational and demographic factors, and the risk of breast cancer (BC) among Egyptian females.

NCT ID: NCT04115137 Recruiting - Observational Study Clinical Trials

Pelvic Varicose Veins Treated With Vascular Plugs Type Amplatzer: REPiVAC

REPiVAC
Start date: March 1, 2019
Phase:
Study type: Observational [Patient Registry]

Spanish multicentric record to study the efficacy and safety of the treatment with plugs in Pelvic Congestion Syndrome.

NCT ID: NCT03995849 Completed - Observational Study Clinical Trials

Motion of Kids on Radiation Treatment

Start date: October 29, 2019
Phase:
Study type: Observational

At Princess Margaret Cancer Centre, a comprehensive approach to help children stay still during radiation treatment (RT) such as audio-visual distraction (television) is routinely used. These techniques help reduce the need for sedation or general anaesthesia to keep children still to avoid the chance of missing the tumour during RT. This approach has not been systematically evaluated to determine its effectiveness at reducing movement of children receiving RT. The purpose of the study is to measure the movement of children between the beginning and the end of RT to see how much they moved during treatment.

NCT ID: NCT03869645 Terminated - Observational Study Clinical Trials

CAPERE Thrombectomy System Post-Market Clinical Follow Up Study

Start date: June 1, 2019
Phase:
Study type: Observational

A prospective, single-arm, non-blinded study, intending to collect and evaluate data in up to forty (40) human subjects with acute thrombosis, treated with the CAPEREā„¢ Thrombectomy System.

NCT ID: NCT03417804 Completed - Clinical trials for Neuromuscular Blockade

Incidence of Postoperative Residual Neuromuscular Blockade in Portugal

Start date: June 18, 2018
Phase:
Study type: Observational

This is an epidemiological multicenter, observational, prospective study, designed to determine the incidence of postoperative residual neuromuscular blockade - defined by a TOF (train-of-four) ratio < 0.9 - at PACU arrival. Subjects aged at least 18 years old (n=360) admitted for different types of elective surgical procedures requiring general anesthesia with neuromuscular blocking agents will be included.

NCT ID: NCT03233789 Completed - Neurologic Disorder Clinical Trials

Development and Validation of an ADL-score Based on FIM and EBI

EVA
Start date: November 1, 2015
Phase:
Study type: Observational

The aim of this mixed-methods-study is to develop and validate an algorithm to transform FIM (Functional Independence Measure) and EBI (Extended Barthel Index) into an ADL score (Activities of Daily Life) that can be used to compare outcome quality of rehabilitation clinics. The following steps are performed: 1. Development of an ADL-algorithms by experts 2. Validation of the ADL-algorithms in a quantitative approach 3. Finalization of the ADL-algorithms by experts based on study results