The Effect of the DASH Diet Containing Meat on Muscle and Metabolic Health in Older Adults

Obesity Clinical Trial

Official title:

The Effect of Meat Intake as a Part of the DASH Diet on Indices of Muscular Fitness, Body Composition and Metabolic Health in Adults 65 and Older: A Controlled-Feeding Systems-Biology Study

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT04127240
• Other study ID #: 1712006
• Status: Completed
• Phase: N/A
• Start date: June 15, 2017
• Est. completion date: November 10, 2018

Study information

• Verified date: October 2019
• Source: South Dakota State University
• Contact: n/a
• Is FDA regulated: No
• Study type: Interventional

Clinical Trial Summary

Age-related changes in body composition, muscular fitness, and metabolic health resulting in the onset of obesity, sarcopenia, and chronic diseases are profound public health issues that are in need of immediate attention. Effective and feasible methods, such as dietary therapies, are needed to improve health in older adults that in turn lead to independence, enhanced quality of life and reduced hospitalizations. Diet quality and dietary protein intake are vital for maintaining body composition, muscle mass and improved physical performance. Malnutrition in dietary protein intake is a major cause of reduced muscle mass, strength, and function in older adults. The Dietary Approaches to Stop Hypertension (DASH) dietary pattern is a high-quality therapeutic diet known to improve health status in various diverse and at-risk populations resulting in improved heart health, maintained cognitive function and reductions in metabolic diseases such as diabetes, metabolic syndrome, and nonalcoholic fatty liver disease. The primary protein recommendations of the DASH diet are poultry and fish and it is recommended to decrease or exclude red meats from the diet. However, studies have demonstrated that lean red meat incorporated into a DASH-like diet doesn't exacerbate cardiovascular health indices in adults, indicating that lean red meat can be included in the DASH diet without negative effects on heart health. Although studies have reported on the DASH diet in older adults, no studies have investigated the effect of the DASH diet containing lean red meat on measures of body composition, muscle mass or metabolic health under controlled-feeding conditions. The purpose of this study was to determine the effect of the DASH diet containing daily intakes of lean red meat on indicators of body composition, muscular fitness and biomarkers of metabolic health in adults 65 and older using controlled-feeding and systems biology approaches.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 46
• Est. completion date: November 10, 2018
• Est. primary completion date: November 10, 2018
• Accepts healthy volunteers: Accepts Healthy Volunteers
• Gender: All
• Age group: 65 Years and older

Eligibility

Inclusion Criteria:

• 65 and older

• Upward mobile ability

Exclusion Criteria:

• Under the age of 65

• Immobility

Related Conditions & MeSH terms

• Aging
• Obesity
• Sarcopenia

Intervention

Other:
• DASH diet containing daily intakes of red meat
Each participant was randomized to consume 3 or 6 ounces of red meat as a part of the DASH dietary pattern for 12-weeks.

Locations

Country	Name	City	State
United States	South Dakota State University	Brookings	South Dakota

Sponsors (1)

Lead Sponsor	Collaborator
South Dakota State University

Country where clinical trial is conducted

United States, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Body weight	Measured by bioelectrical impedance	Change in body weight from baseline to 3 months
Primary	Hand grip strength	Measured by a hand-held dynamometer	Change in strength from baseline to 3 months
Primary	Glucose	Measure serum glucose using colorimetry assay	Change in glucose concentrations from baseline to 3 months