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Clinical Trial Details — Status: Completed

Administrative data

NCT number NCT03868683
Other study ID # 2016/00926
Secondary ID
Status Completed
Phase N/A
First received
Last updated
Start date August 20, 2018
Est. completion date April 17, 2019

Study information

Verified date March 2019
Source Clinical Nutrition Research Centre, Singapore
Contact n/a
Is FDA regulated No
Health authority
Study type Interventional

Clinical Trial Summary

To investigate the effect of added sugar to bake beans on glycemic and insulinemic response.


Description:

There will be a total of 7 test session. Each session will last for 3 hours. At each test session, volunteers will be served with 7 test meals and blood will be collected. After an overnight fast, subjects will visit the research center. Two fasting capillary blood samples will be collected via fingerpick. Following the fasting samples, volunteers will consume the test meals. Further blood samples will be collected at 15, 30, 45, 60, 90, 120, 150, 180 minutes after the ingestion of test meal. These samples will be used to analyses for whole capillary blood glucose. At every 30 minute interval, samples will be collected for analysis of capillary plasma insulin.


Recruitment information / eligibility

Status Completed
Enrollment 12
Est. completion date April 17, 2019
Est. primary completion date April 17, 2019
Accepts healthy volunteers Accepts Healthy Volunteers
Gender Male
Age group 21 Years to 60 Years
Eligibility Inclusion Criteria:

- Chinese ethnicity

- Age =21 and = 60 years

- Body mass index between 18.5 to 25 kg/m2

- Normal blood pressure <140/90 mmHg

- Fasting blood glucose <6.0 mmol/L

- In general good health

Exclusion Criteria:

- Current Smoker

- have any metabolic diseases (such as diabetes, hypertension etc)

- have known glucose-6-phosphate dehydrogenase deficiency (G6PD deficiency)

- having medical conditions and/or taking medications known to affect glycaemia (glucocorticoids, thyroid hormones, thiazide diuretics)

- have intolerances or allergies to any foods

- partake in sports at the competitive and/or endurance levels

- intentionally restrict food intake

Study Design


Intervention

Other:
Glucose Reference 1
30 g of glucose dissolved in 250 ml of water
Glucose Reference 2
30 g of glucose dissolved in 250 ml of water
Glucose reference 3
30 g of glucose dissolved in 250 ml of water
Sucrose
30 g of Sucrose dissolved in 250 ml of water
Regular Bake beans in tomato sauce
Bake beans in tomato sauce containing 14 g of sugar
Bake beans in tomato sauce, reduced sugar
Bake beans in tomato sauce containing 12.2 g of sugar
Bake beans in tomato sauce, low GI
Bake beans in tomato sauce containing 7.2 g of sugar

Locations

Country Name City State
Singapore Clinical Nutrition Research Centre Singapore

Sponsors (1)

Lead Sponsor Collaborator
Clinical Nutrition Research Centre, Singapore

Country where clinical trial is conducted

Singapore, 

Outcome

Type Measure Description Time frame Safety issue
Primary Glucose [ Whole capillary blood glucose will be measure using Hemocue analyser Up to 180 minutes
Secondary Insulin Capillary plasma will be measure using Cobas analyser Up to 180 minutes
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