Obesity Clinical Trial
Official title:
Sprint Interval Training: Insulin Sensitivity and Acute-Chronic Metabolic Flexibility in Individuals Living With Obesity: The i-FLEX Study
Regular exercise is a cornerstone in the prevention and the management of cardio-metabolic
risk factors. Some of the beneficial effect of exercise training occurs through metabolic
flexibility' enhancement. Metabolic flexibility is the ability to respond or adapt to
conditional changes in metabolic demand, and previous literature has shown that individuals
living with obesity have an impaired metabolic flexibility compared to lean individuals.
However, there is a lack of empirical evidence on the impact of sprint interval training on
metabolic flexibility and whether this translates into clinically meaningful outcomes.
This study will evaluate the impact of 4-week sprint interval training in normal weight
individuals as well as individuals living with obesity on acute and chronic metabolic
flexibility, irisin secretion and insulin sensitivity.
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