Neck Fat Accumulation and Its Relationship to Cardiovascular Risk and Metabolic Syndrome

Obesity Clinical Trial

Official title:

Compartmental Neck Fat Accumulation and Its Relationship to Cardiovascular Risk and Metabolic Syndrome

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT02205021
• Other study ID #: 2012P001603
• Status: Completed
• Phase: N/A
• First received: July 29, 2014
• Last updated: July 30, 2014
• Start date: January 2014

Study information

• Verified date: July 2014
• Source: Massachusetts General Hospital
• Contact: n/a
• Is FDA regulated: No
• Health authority: United States: Institutional Review Board
• Study type: Observational

Clinical Trial Summary

Accumulation of fat in the neck using tape measures has been linked to increased cardiovascular risk. The investigators' hypothesis is that detailed measures of neck fat using computed tomography will show that specific fat compartments in the neck contribute differently to cardiovascular risk.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 303
• Est. primary completion date: March 2014
• Accepts healthy volunteers: Accepts Healthy Volunteers
• Gender: Both
• Age group: 18 Years to 91 Years

Eligibility

Inclusion Criteria:

• no history of malignancy at the time of image acquisition

• fasting glucose measured immediately prior to PET/CT

Exclusion Criteria:

• history of neck cancer, radiation therapy, and/or surgery

Study Design

Observational Model: Cohort, Time Perspective: Retrospective

Related Conditions & MeSH terms

• Metabolic Syndrome X
• Obesity

Intervention

Other:
• No intervention

Locations

Country	Name	City	State
United States	Massachusetts General Hospital	Boston	Massachusetts

Sponsors (1)

Lead Sponsor	Collaborator
Massachusetts General Hospital

Country where clinical trial is conducted

United States, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Relationship of specific neck compartments to cardiovascular risk	Cardiovascular risk measures were obtained within one year of CT imaging of the neck.	1 year between PET/CT and cardiometabolic marker measures	No