Effects of Aerobic Exercise Detraining

Obesity Clinical Trial

— E-Mechanic_Fol  

Official title:

Effects of Aerobic Exercise Detraining on Energy Balance in Overweight Persons

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT02158130
• Other study ID #: PBRC 2014-028
• Status: Completed
• Phase: N/A
• First received: June 4, 2014
• Last updated: March 21, 2016
• Start date: September 2014
• Est. completion date: March 2016

Study information

• Verified date: March 2016
• Source: Pennington Biomedical Research Center
• Contact: n/a
• Is FDA regulated: No
• Health authority: United States: Institutional Review Board
• Study type: Observational

Clinical Trial Summary

The proposed study seeks to better understand the role of body weight, energy expenditure, and energy intake as mechanisms of body weight gain during detraining following aerobic exercise. It is hypothesized that participants in the higher dose exercise group will have greater body weight gain compared to the lower exercise dose and control group from wk 24 to wk 76 follow-up.

Description:

Eligibility criteria include having successfully completed the main E-Mechanic study, be willing to archive blood samples and not being currently enrolled in another study that may effect body, energy intake or energy expenditure. The investigators will measure body weight, waist/hip circumference, blood pressure, body composition, physical activity, questionnaire about appetite/food intake and physical fitness.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 25
• Est. completion date: March 2016
• Est. primary completion date: March 2016
• Accepts healthy volunteers: Accepts Healthy Volunteers
• Gender: Both
• Age group: 18 Years to 67 Years

Eligibility

Inclusion Criteria:

• Completed the E-Mechanic study

• Be willing to archive blood samples

• Not participating in a study that would alter body weight, energy intake, or energy expenditure.

Study Design

Observational Model: Case Control, Time Perspective: Cross-Sectional

Related Conditions & MeSH terms

• Body Weight
• Motor Activity
• Obesity

Locations

Country	Name	City	State
United States	Pennington Biomedical Research Center	Baton Rouge	Louisiana

Sponsors (1)

Lead Sponsor	Collaborator
Pennington Biomedical Research Center

Country where clinical trial is conducted

United States, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Other	Circumferences	Waist and hip circumferences	Week 64-88 post study randomization	No
Other	Blood Pressure		Week 64-88 post study randomization	No
Other	Body Composition	Whole Body Scan GE iDXA (Dual energy x-ray absorptiometry)	Week 64 - 88 post study randomization	No
Other	Triglycerides		Week 64 - 88 post study randomization	No
Other	Cholesterol	Total, HDL, and LDL cholesterol	Week 64 - 88 post study randomization	No
Primary	Body Weight	Fasting body weight	Week 64 - 88 post study randomization	No
Secondary	Energy Expenditure	Energy expenditure is calculated with the Sensewear Armband.	Week 64 - 90 since study randomization	No
Secondary	Energy Intake	Energy expenditure is calculated with the Sensewear Armband and furthermore, energy intake is calculated by adjusting TDEE for change in body weight following the methods used in doubly labeled water adjustment.	Week 64 - 90 post study randomization	No